{"id":2752,"date":"2026-10-08T15:05:59","date_gmt":"2026-10-08T06:05:59","guid":{"rendered":"https:\/\/oncoc.showa.gunma-u.ac.jp\/?p=2752"},"modified":"2026-10-08T15:05:59","modified_gmt":"2026-10-08T06:05:59","slug":"%e3%80%90new%e3%80%91%e4%bb%8a%e9%80%b1%e3%81%ae%e8%85%ab%e7%98%8d%e5%86%85%e7%a7%919-28-10-4","status":"publish","type":"post","link":"https:\/\/oncoc.showa.gunma-u.ac.jp\/?p=2752","title":{"rendered":"<b>\u3010NEW\u3011<\/b>\u4eca\u9031\u306e\u816b\u760d\u5185\u79d1(9\/28-10\/4)"},"content":{"rendered":"<p>\u4eca\u9031\u306e\u816b\u760d\u5185\u79d1\uff082026\u5e7410\u6708\u7b2c1\u9031\uff0f9\u670828\u65e5\u301c10\u67084\u65e5\uff09<br \/>\n\u7fa4\u99ac\u5927\u5b66\u533b\u5b66\u90e8\u9644\u5c5e\u75c5\u9662 \u816b\u760d\u5185\u79d1<\/p>\n<p>&nbsp;<\/p>\n<p>\u816b\u760d\u5185\u79d1\u306b\u95a2\u5fc3\u306e\u3042\u308b\u533b\u5b66\u751f\u30fb\u7814\u4fee\u533b\u306e\u65b9\u3078\u3002\u5f53\u79d1\u306e\u4e00\u9031\u9593\u3068\u3001\u304c\u3093\u85ac\u7269\u7642\u6cd5\u3092\u3081\u3050\u308b\u52d5\u304d\u3092\u6bce\u9031\u304a\u4f1d\u3048\u3057\u307e\u3059\u3002<\/p>\n<p>\u4eca\u9031\u306f\u30019\u670824\u65e5\u306b\u7c73\u56fd\u3067\u627f\u8a8d\u3055\u308c\u305f\u814e\u7d30\u80de\u304c\u3093\u306e\u98f2\u307f\u85ac\u306e\u7d44\u307f\u5408\u308f\u305b\uff08\u65e5\u672c\u306f\u7533\u8acb\u4e2d\uff09\u3092\u53d6\u308a\u4e0a\u3052\u307e\u3059\u3002\u300c\u304c\u3093\u304c\u9032\u3080\u307e\u3067\u306e\u671f\u9593\u306f\u5ef6\u3073\u305f\u304c\u3001\u751f\u5b58\u671f\u9593\u306b\u306f\u6709\u610f\u306a\u5dee\u304c\u51fa\u306a\u304b\u3063\u305f\u300d\u7d50\u679c\u3092\u3069\u3046\u8aad\u3080\u304b\u3092\u3001\u814e\u7d30\u80de\u304c\u3093\u3068\u300c\u9178\u7d20\u30bb\u30f3\u30b5\u30fc\u300d\u306e\u95a2\u4fc2\u3068\u3042\u308f\u305b\u3066\u898b\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500<br \/>\n\u25a0 \u4eca\u9031\u306e\u5f53\u79d1\u304b\u3089<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u304c\u3093\u30b2\u30ce\u30e0\u533b\u7642\u306e\u30a8\u30ad\u30b9\u30d1\u30fc\u30c8\u30d1\u30cd\u30eb<br \/>\n\u304c\u3093\u907a\u4f1d\u5b50\u30d1\u30cd\u30eb\u691c\u67fb\u306e\u7d50\u679c\u3092\u3082\u3068\u306b\u3001\u816b\u760d\u5185\u79d1\u30fb\u75c5\u7406\u30fb\u907a\u4f1d\u306e\u5c02\u9580\u5bb6\u306a\u3069\u304c\u96c6\u307e\u3063\u3066\u6cbb\u7642\u306e\u9078\u629e\u80a2\u3092\u691c\u8a0e\u3059\u308b\u30a8\u30ad\u30b9\u30d1\u30fc\u30c8\u30d1\u30cd\u30eb\u304c\u958b\u304b\u308c\u3001\u5f53\u79d1\u3082\u53c2\u52a0\u3057\u307e\u3057\u305f\u3002\u524d\u306e\u9031\u306b\u884c\u3046\u4e0b\u8aad\u307f\u4f1a\u3067\u78ba\u304b\u3081\u305f\u5185\u5bb9\u3092\u8e0f\u307e\u3048\u3066\u3001\u4e00\u4f8b\u305a\u3064\u7d50\u8ad6\u3092\u307e\u3068\u3081\u3066\u3044\u304d\u307e\u3059\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u30d1\u30cd\u30eb\u691c\u67fb\u306e\u5831\u544a\u66f8\u306f\u3001\u898b\u3064\u304b\u3063\u305f\u907a\u4f1d\u5b50\u306e\u5909\u5316\u3092\u4e26\u3079\u305f\u4e00\u89a7\u306b\u3059\u304e\u307e\u305b\u3093\u3002\u305d\u308c\u305e\u308c\u306e\u5909\u5316\u306b\u610f\u5473\u304c\u3042\u308b\u306e\u304b\u3001\u4f7f\u3048\u308b\u85ac\u3084\u81e8\u5e8a\u8a66\u9a13\u304c\u3042\u308b\u306e\u304b\u3092\u3001\u5c02\u9580\u306e\u9055\u3046\u4eba\u305f\u3061\u3067\u8a71\u3057\u5408\u3063\u3066\u521d\u3081\u3066\u3001\u60a3\u8005\u3055\u3093\u306b\u8fd4\u305b\u308b\u300c\u7b54\u3048\u300d\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u81e8\u5e8a\u7814\u7a76\u306e\u8a08\u753b\u3092\u3001\u9662\u5185\u306e\u5be9\u67fb\u59d4\u54e1\u4f1a\u3067\u8aac\u660e<br \/>\n\u5f53\u79d1\u304c\u8a08\u753b\u3057\u3066\u3044\u308b\u81e8\u5e8a\u7814\u7a76\u306b\u3064\u3044\u3066\u3001\u9662\u5185\u306e\u5be9\u67fb\u59d4\u54e1\u4f1a\u3067\u76ee\u7684\u3084\u65b9\u6cd5\u3092\u8aac\u660e\u3057\u307e\u3057\u305f\u3002\u59d4\u54e1\u4f1a\u306b\u306f\u533b\u7642\u4ee5\u5916\u306e\u5206\u91ce\u306e\u59d4\u54e1\u3082\u52a0\u308f\u3063\u3066\u3044\u308b\u305f\u3081\u3001\u5c02\u9580\u7528\u8a9e\u306b\u983c\u3089\u306a\u3044\u8aac\u660e\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u81e8\u5e8a\u7814\u7a76\u306f\u3001\u60a3\u8005\u3055\u3093\u306e\u5354\u529b\u304c\u3042\u3063\u3066\u521d\u3081\u3066\u6210\u308a\u7acb\u3061\u307e\u3059\u3002\u7814\u7a76\u306e\u610f\u7fa9\u3084\u3001\u53c2\u52a0\u3055\u308c\u308b\u65b9\u306e\u6a29\u5229\u3068\u500b\u4eba\u60c5\u5831\u3092\u3069\u3046\u5b88\u308b\u304b\u3092\u7b2c\u4e09\u8005\u306b\u8aac\u660e\u3057\u3001\u8a8d\u3081\u3066\u3082\u3089\u3046\u624b\u7d9a\u304d\u306f\u3001\u7814\u7a76\u306e\u51fa\u767a\u70b9\u3067\u3059\u3002\u5c02\u9580\u5916\u306e\u4eba\u306b\u308f\u304b\u308b\u8a00\u8449\u3067\u8aac\u660e\u3059\u308b\u3053\u3068\u306f\u3001\u81ea\u5206\u306e\u8a08\u753b\u3092\u898b\u76f4\u3059\u6a5f\u4f1a\u306b\u3082\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u5185\u79d1\u30b0\u30e9\u30f3\u30c9\u30ab\u30f3\u30d5\u30a1\u30ec\u30f3\u30b9\uff08M&amp;M \u30ab\u30f3\u30d5\u30a1\u30ec\u30f3\u30b9\uff09<br \/>\n\u5185\u79d1\u306e\u5404\u8a3a\u7642\u79d1\u304c\u96c6\u307e\u308b\u30b0\u30e9\u30f3\u30c9\u30ab\u30f3\u30d5\u30a1\u30ec\u30f3\u30b9\u306b\u53c2\u52a0\u3057\u307e\u3057\u305f\u3002\u4eca\u56de\u306f\u3001\u7d4c\u904e\u304c\u601d\u308f\u3057\u304f\u306a\u304b\u3063\u305f\u75c7\u4f8b\u3092\u632f\u308a\u8fd4\u308a\u3001\u6b21\u306b\u751f\u304b\u305b\u308b\u70b9\u3092\u5168\u54e1\u3067\u8003\u3048\u308b M&amp;M\uff08Morbidity &amp; Mortality\uff09\u30ab\u30f3\u30d5\u30a1\u30ec\u30f3\u30b9\u306e\u5f62\u5f0f\u3067\u3057\u305f\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u304c\u3093\u85ac\u7269\u7642\u6cd5\u3092\u53d7\u3051\u308b\u60a3\u8005\u3055\u3093\u306f\u3001\u814e\u81d3\u30fb\u5fc3\u81d3\u30fb\u611f\u67d3\u75c7\u306a\u3069\u3001\u5185\u79d1\u306e\u3042\u3089\u3086\u308b\u554f\u984c\u3092\u62b1\u3048\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u5c02\u9580\u306e\u9055\u3046\u5185\u79d1\u533b\u304c\u540c\u3058\u5834\u3067\u4e00\u3064\u306e\u7d4c\u904e\u3092\u632f\u308a\u8fd4\u308b\u6a5f\u4f1a\u306f\u3001\u816b\u760d\u5185\u79d1\u533b\u306b\u3068\u3063\u3066\u3082\u3001\u5185\u79d1\u533b\u3068\u3057\u3066\u306e\u571f\u53f0\u3092\u5e83\u3052\u308b\u5834\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u203b \u500b\u3005\u306e\u60a3\u8005\u3055\u3093\u30fb\u75c7\u4f8b\u306b\u95a2\u3059\u308b\u60c5\u5831\u306f\u542b\u307f\u307e\u305b\u3093\u3002\u5f53\u79d1\u306e\u6d3b\u52d5\u3092\u4e00\u822c\u5316\u3057\u3066\u3054\u7d39\u4ecb\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500<\/p>\n<p>\u25a0 \u4eca\u9031\u306e\u816b\u760d\u5185\u79d1\u30cb\u30e5\u30fc\u30b9<\/p>\n<p>\u203b \u5bfe\u8c61\u9031\uff089\u670828\u65e5\u301c10\u67084\u65e5\uff09\u306b\u3001\u56fd\u5185\u3067\u816b\u760d\u9818\u57df\u306e\u65b0\u305f\u306a\u85ac\u4e8b\u627f\u8a8d\u30fb\u85ac\u4fa1\u53ce\u8f09\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\uff08PMDA \u306e\u627f\u8a8d\u54c1\u76ee\u4e00\u89a7\u3067\u78ba\u8a8d\u3067\u304d\u305f\u76f4\u8fd1\u306e\u627f\u8a8d\u65e5\u306f9\u670816\u65e5\uff09\u3002\u4eca\u9031\u306f\u7c73\u56fd\u3067\u306e\u627f\u8a8d\u3092\u53d6\u308a\u4e0a\u3052\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u814e\u7d30\u80de\u304c\u3093\u306b\u3001HIF-2\u03b1 \u963b\u5bb3\u85ac\u30d9\u30eb\u30ba\u30c1\u30d5\u30a1\u30f3\u3068\u30ec\u30f3\u30d0\u30c1\u30cb\u30d6\u306e\u4f75\u7528 \u2015 \u7c73\u56fd\u3067\u627f\u8a8d\u3014\u7c73\u56fdFDA\u627f\u8a8d\uff0f\u65e5\u672c\u306f\u627f\u8a8d\u7533\u8acb\u4e2d\u3015<br \/>\n2026\u5e749\u670824\u65e5\u3001\u7c73\u56fd\u98df\u54c1\u533b\u85ac\u54c1\u5c40\uff08FDA\uff09\u306f\u3001\u30d9\u30eb\u30ba\u30c1\u30d5\u30a1\u30f3\uff08\u8ca9\u58f2\u540d \u30a6\u30a7\u30ea\u30ec\u30b0\uff09\u3068\u30ec\u30f3\u30d0\u30c1\u30cb\u30d6\uff08\u8ca9\u58f2\u540d \u30ec\u30f3\u30d3\u30de\uff09\u306e\u4f75\u7528\u7642\u6cd5\u3092\u627f\u8a8d\u3057\u307e\u3057\u305f\u3002\u5bfe\u8c61\u306f\u3001\u9032\u884c\u3057\u305f\u814e\u7d30\u80de\u304c\u3093\uff08\u6de1\u660e\u7d30\u80de\u306e\u6210\u5206\u3092\u3082\u3064\u3082\u306e\uff09\u306e\u6210\u4eba\u3067\u3001\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\uff08PD-1\uff0fPD-L1 \u963b\u5bb3\u85ac\uff09\u306b\u3088\u308b\u6cbb\u7642\u3092\u53d7\u3051\u305f\u3042\u3068\u306e\u65b9\u3067\u3059\u3002\u7528\u6cd5\u306f\u3001\u30ec\u30f3\u30d0\u30c1\u30cb\u30d620mg\u3068\u30d9\u30eb\u30ba\u30c1\u30d5\u30a1\u30f3120mg\u3092\u3044\u305a\u308c\u30821\u65e51\u56de\u5185\u670d\u3057\u307e\u3059\u3002\u56fd\u5185\u3067\u306f9\u670828\u65e5\u306b\u3001\u30ec\u30f3\u30d0\u30c1\u30cb\u30d6\u306e\u88fd\u9020\u8ca9\u58f2\u5143\u3067\u3042\u308b\u30a8\u30fc\u30b6\u30a4\u304c\u3053\u306e\u627f\u8a8d\u3092\u767a\u8868\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n\u6839\u62e0\u3068\u306a\u3063\u305f\u306e\u306f\u3001\u30ab\u30dc\u30b6\u30f3\u30c1\u30cb\u30d6\u3068\u6bd4\u3079\u305f\u7b2c\u2162\u76f8\u306e LITESPARK-011 \u8a66\u9a13\uff08747\u4f8b\uff09\u3067\u3059\u3002\u304c\u3093\u304c\u9032\u884c\u3059\u308b\u307e\u3067\u306e\u671f\u9593\uff08\u7121\u5897\u60aa\u751f\u5b58\u671f\u9593\uff09\u3068\u594f\u52b9\u7387\u306f\u4f75\u7528\u7642\u6cd5\u304c\u4e0a\u56de\u308a\u3001\u5168\u751f\u5b58\u671f\u9593\u306f\u6700\u7d42\u89e3\u6790\u3067\u3082\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u306a\u5dee\u3092\u793a\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3014FDA\u767a\u8868\u3015\u3002\u8a73\u3057\u3044\u6570\u5024\u306f\u300c\u4eca\u9031\u306e\u4e00\u5831\u300d\u3067\u7d39\u4ecb\u3057\u307e\u3059\u3002\u6ce8\u610f\u3059\u3079\u304d\u526f\u4f5c\u7528\u3068\u3057\u3066\u3001\u30d9\u30eb\u30ba\u30c1\u30d5\u30a1\u30f3\u3067\u306f\u80ce\u5150\u3078\u306e\u5f71\u97ff\uff08\u7c73\u56fd\u6dfb\u4ed8\u6587\u66f8\u306e\u67a0\u56f2\u307f\u8b66\u544a\uff09\u3001\u8ca7\u8840\u3001\u4f4e\u9178\u7d20\u304c\u3001\u4f75\u7528\u3067\u306f\u5fc3\u6a5f\u80fd\u969c\u5bb3\u304c\u6319\u3052\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u65e5\u672c\u3067\u306f\u3001\u30d9\u30eb\u30ba\u30c1\u30d5\u30a1\u30f3\u306f\u3059\u3067\u306b\u300c\u304c\u3093\u5316\u5b66\u7642\u6cd5\u5f8c\u306b\u5897\u60aa\u3057\u305f\u6839\u6cbb\u5207\u9664\u4e0d\u80fd\u53c8\u306f\u8ee2\u79fb\u6027\u306e\u814e\u7d30\u80de\u764c\u300d\u3068\u300c\u30d5\u30a9\u30f3\u30fb\u30d2\u30c3\u30da\u30eb\u30fb\u30ea\u30f3\u30c9\u30a6\u75c5\u95a2\u9023\u816b\u760d\u300d\u306b\u5bfe\u3057\u3066\u5358\u5264\u3067\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30ec\u30f3\u30d0\u30c1\u30cb\u30d6\u3068\u306e\u4f75\u7528\u306b\u3064\u3044\u3066\u306f\u30012026\u5e743\u670827\u65e5\u306b\u30a8\u30fc\u30b6\u30a4\u3068 MSD \u304c\u56fd\u5185\u3067\u7528\u6cd5\u30fb\u7528\u91cf\u306e\u8ffd\u52a0\u3092\u7533\u8acb\u3057\u305f\u3068\u767a\u8868\u3057\u3066\u304a\u308a\u3001\u4f5c\u6210\u6642\u70b9\u3067\u306f\u56fd\u5185\u627f\u8a8d\u306e\u516c\u8868\u306f\u78ba\u8a8d\u3067\u304d\u3066\u3044\u307e\u305b\u3093\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u814e\u7d30\u80de\u304c\u3093\u3067\u306f\u3001\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\u3092\u542b\u3080\u6cbb\u7642\u304c\u4e00\u6b21\u6cbb\u7642\u306e\u4e2d\u5fc3\u306b\u306a\u308a\u3001\u300c\u514d\u75ab\u7642\u6cd5\u306e\u3042\u3068\u3001\u6b21\u306b\u4f55\u3092\u4f7f\u3046\u304b\u300d\u304c\u5927\u304d\u306a\u8ab2\u984c\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u7d44\u307f\u5408\u308f\u305b\u306e\u8003\u3048\u65b9\u306f\u300c\u3072\u3068\u3053\u3068\u30b3\u30e9\u30e0\u300d\u3067\u7d39\u4ecb\u3057\u307e\u3059\u3002<br \/>\n\u51fa\u5178\uff1aU.S. Food and Drug Administration\u300c<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.fda.gov\/drugs\/resources-information-approved-drugs\/fda-approves-belzutifan-combination-lenvatinib-advanced-renal-cell-carcinoma-clear-cell-component&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E\" target=\"_blank\" rel=\"noopener\">FDA approves belzutifan in combination with lenvatinib for advanced renal cell carcinoma with a clear cell component<\/a>\u300d\uff082026\u5e749\u670824\u65e5\uff09 \uff0f <a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.eisai.co.jp\/news\/2026\/news202653.html&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E\" target=\"_blank\" rel=\"noopener\">\u30a8\u30fc\u30b6\u30a4\u682a\u5f0f\u4f1a\u793e \u30cb\u30e5\u30fc\u30b9\u30ea\u30ea\u30fc\u30b9<\/a>\uff082026\u5e749\u670828\u65e5\uff09 \uff0f MSD\u682a\u5f0f\u4f1a\u793e \u30cb\u30e5\u30fc\u30b9\u30ea\u30ea\u30fc\u30b9\u300c<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.msd.co.jp\/news\/product-news-20260327\/&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E\" target=\"_blank\" rel=\"noopener\">\u300c\u30ec\u30f3\u30d3\u30de\u00ae\u300d\uff08\u30ec\u30f3\u30d0\u30c1\u30cb\u30d6\uff09\u306b\u3064\u3044\u3066\u3001\u65e5\u672c\u306b\u304a\u3044\u3066\u3001\u304c\u3093\u5316\u5b66\u7642\u6cd5\u5f8c\u306b\u5897\u60aa\u3057\u305f\u814e\u7d30\u80de\u304c\u3093\u3092\u5bfe\u8c61\u306b\u300c\u30a6\u30a7\u30ea\u30ec\u30b0\u00ae\u300d\uff08\u30d9\u30eb\u30ba\u30c1\u30d5\u30a1\u30f3\uff09\u3068\u306e\u4f75\u7528\u7642\u6cd5\u306b\u4fc2\u308b\u7528\u6cd5\u30fb\u7528\u91cf\u3092\u8ffd\u52a0\u7533\u8acb<\/a>\u300d\uff082026\u5e743\u670827\u65e5\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\u306e\u300c\u91cd\u5927\u306a\u526f\u4f5c\u7528\u300d\u306b\u3001\u3076\u3069\u3046\u819c\u708e\u306a\u3069\u304c\u8ffd\u52a0\u3055\u308c\u307e\u3057\u305f<br \/>\n\u539a\u751f\u52b4\u50cd\u7701\u306e\u300c\u533b\u85ac\u54c1\u30fb\u533b\u7642\u6a5f\u5668\u7b49\u5b89\u5168\u6027\u60c5\u5831 No.432\u300d\uff082026\u5e749\u6708\uff09\u304c\u300110\u67082\u65e5\u306b\u65e5\u672c\u81e8\u5e8a\u816b\u760d\u5b66\u4f1a\u306e\u304a\u77e5\u3089\u305b\u6b04\u3067\u3082\u5468\u77e5\u3055\u308c\u307e\u3057\u305f\u30028\u670825\u65e5\u306b\u6539\u8a02\u304c\u6307\u793a\u3055\u308c\u305f\u6dfb\u4ed8\u6587\u66f8\u306e\u300c\u91cd\u5927\u306a\u526f\u4f5c\u7528\u300d\u306e\u3046\u3061\u3001\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\u306b\u95a2\u308f\u308b\u3082\u306e\u3068\u3057\u3066\u3001\u6b21\u306e\u9805\u76ee\u304c\u65b0\u305f\u306b\u52a0\u308f\u3063\u3066\u3044\u307e\u3059\u3002<br \/>\n\u30fb\u3076\u3069\u3046\u819c\u708e\uff1a\u30a2\u30d9\u30eb\u30de\u30d6\u3001\u30a2\u30c6\u30be\u30ea\u30ba\u30de\u30d6\u3001\u30c7\u30e5\u30eb\u30d0\u30eb\u30de\u30d6\u3001\u30c8\u30ec\u30e1\u30ea\u30e0\u30de\u30d6\uff08\u773c\u306e\u7570\u5e38\u306e\u6709\u7121\u3092\u5b9a\u671f\u7684\u306b\u78ba\u8a8d\u3057\u3001\u7570\u5e38\u304c\u3042\u308c\u3070\u901f\u3084\u304b\u306b\u53d7\u8a3a\u3059\u308b\u3088\u3046\u60a3\u8005\u3055\u3093\u306b\u4f1d\u3048\u308b\u3053\u3068\u3082\u3001\u6ce8\u610f\u4e8b\u9805\u306b\u52a0\u308f\u308a\u307e\u3057\u305f\uff09<br \/>\n\u30fb\u8840\u7403\u8caa\u98df\u6027\u30ea\u30f3\u30d1\u7d44\u7e54\u7403\u75c7\uff1a\u30c1\u30b9\u30ec\u30ea\u30ba\u30de\u30d6\u3001\u30ec\u30c1\u30d5\u30a1\u30f3\u30ea\u30de\u30d6\u3001\u30a2\u30d9\u30eb\u30de\u30d6\u3001\u30c7\u30e5\u30eb\u30d0\u30eb\u30de\u30d6\u3001\u30a4\u30d4\u30ea\u30e0\u30de\u30d6\u3001\u30c8\u30ec\u30e1\u30ea\u30e0\u30de\u30d6<br \/>\n\u30fb\u514d\u75ab\u53cd\u5fdc\u306b\u3088\u308b\u91cd\u5ea6\u306e\u80c3\u708e\u30fb\u98df\u9053\u708e\uff1a\u30cb\u30dc\u30eb\u30de\u30d6<br \/>\n\u6539\u8a02\u306e\u6839\u62e0\u3068\u306a\u3063\u305f\u56fd\u5185\u306e\u5831\u544a\u75c7\u4f8b\uff08\u85ac\u3068\u306e\u56e0\u679c\u95a2\u4fc2\u304c\u5426\u5b9a\u3067\u304d\u306a\u3044\u3082\u306e\uff09\u306f\u3001\u85ac\u3054\u3068\u306b0\u301c6\u4f8b\u3067\u3057\u305f\u3014\u5b9f\u30c7\u30fc\u30bf\u3015\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\u306e\u526f\u4f5c\u7528\uff08\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff09\u306f\u3001\u4f53\u306e\u3069\u3053\u306b\u3067\u3082\u8d77\u3053\u308a\u3048\u307e\u3059\u3002\u300c\u76ee\u304c\u304b\u3059\u3080\u300d\u300c\u71b1\u304c\u7d9a\u304f\u300d\u300c\u98f2\u307f\u8fbc\u3080\u3068\u304d\u306b\u3057\u307f\u308b\u30fb\u3064\u304b\u3048\u308b\u300d\u3068\u3044\u3063\u305f\u8a34\u3048\u306e\u80cc\u666f\u306b\u3001\u514d\u75ab\u306e\u526f\u4f5c\u7528\u304c\u96a0\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u983b\u5ea6\u306e\u4f4e\u3044\u3082\u306e\u307b\u3069\u3001\u77e5\u3063\u3066\u3044\u306a\u3051\u308c\u3070\u6c17\u3065\u3051\u307e\u305b\u3093\u3002\u5f53\u79d1\u3067\u306f\u3001\u533b\u5e2b\u30fb\u770b\u8b77\u5e2b\u30fb\u85ac\u5264\u5e2b\u304c\u9023\u643a\u3057\u3066\u3001\u3053\u3046\u3057\u305f\u526f\u4f5c\u7528\u306e\u65e9\u671f\u767a\u898b\u3068\u5bfe\u5fdc\u306b\u3042\u305f\u3063\u3066\u3044\u307e\u3059\u3002<br \/>\n\u51fa\u5178\uff1a\u539a\u751f\u52b4\u50cd\u7701 \u533b\u85ac\u5c40\u300c<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.mhlw.go.jp\/content\/001752947.pdf&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E\" target=\"_blank\" rel=\"noopener\">\u533b\u85ac\u54c1\u30fb\u533b\u7642\u6a5f\u5668\u7b49\u5b89\u5168\u6027\u60c5\u5831 No.432<\/a>\u300d\uff08\u4ee4\u548c8\u5e74\u30142026\u5e74\u30159\u6708\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500<\/p>\n<p>\u25a0 \u4eca\u9031\u306e\u4e00\u5831\uff08\u6ce8\u76ee\u8ad6\u6587\uff09\u3014\u814e\u7d30\u80de\u304c\u3093\uff0f\u5206\u5b50\u6a19\u7684\u6cbb\u7642\u3015<\/p>\n<p>\u514d\u75ab\u7642\u6cd5\u306e\u3042\u3068\u306e\u814e\u7d30\u80de\u304c\u3093\u3067\u3001\u30d9\u30eb\u30ba\u30c1\u30d5\u30a1\u30f3\uff0b\u30ec\u30f3\u30d0\u30c1\u30cb\u30d6\u3092\u30ab\u30dc\u30b6\u30f3\u30c1\u30cb\u30d6\u3068\u6bd4\u3079\u305f\u7b2c\u2162\u76f8\u8a66\u9a13\uff08LITESPARK-011\uff09<br \/>\nLancet. 2026;408(10557):808\u2013820.\uff0f\u7b2c\u2162\u76f8\u30fb\u975e\u76f2\u691c\u30fb\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\uff08NCT04586231\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb25\u304b\u56fd184\u65bd\u8a2d\u3067\u3001\u6297 PD-1\uff0fPD-L1 \u6297\u4f53\u306b\u3088\u308b\u6cbb\u7642\u5f8c\u306b\u9032\u884c\u3057\u305f\u6de1\u660e\u7d30\u80de\u578b\u814e\u7d30\u80de\u304c\u3093747\u4f8b\u3092\u3001\u30d9\u30eb\u30ba\u30c1\u30d5\u30a1\u30f3120mg\uff0b\u30ec\u30f3\u30d0\u30c1\u30cb\u30d620mg\uff08371\u4f8b\uff09\u3068\u3001\u30ab\u30dc\u30b6\u30f3\u30c1\u30cb\u30d660mg\uff08376\u4f8b\uff09\u306b1:1\u3067\u5272\u308a\u4ed8\u3051\u307e\u3057\u305f\u3002\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306f\u3001\u7121\u5897\u60aa\u751f\u5b58\u671f\u9593\uff08\u72ec\u7acb\u3057\u305f\u4e2d\u592e\u5224\u5b9a\uff09\u3068\u5168\u751f\u5b58\u671f\u9593\u306e2\u3064\u3067\u3059\u3002\u8457\u8005\u306b\u306f\u3001\u4e5d\u5dde\u5927\u5b66\u306e\u7814\u7a76\u8005\u3082\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u30fb\u7b2c2\u56de\u4e2d\u9593\u89e3\u6790\uff08\u8ffd\u8de1\u671f\u9593\u4e2d\u592e\u502429.0\u304b\u6708\uff09\u3067\u3001\u7121\u5897\u60aa\u751f\u5b58\u671f\u9593\u306e\u4e2d\u592e\u5024\u306f14.8\u304b\u6708 \u5bfe 10.7\u304b\u6708\uff08\u30cf\u30b6\u30fc\u30c9\u6bd4 0.70\u300195%CI 0.59\u301c0.84\u3001\u7247\u5074 p&lt;0.0001\uff09\u3068\u3001\u4f75\u7528\u7642\u6cd5\u3067\u6709\u610f\u306b\u5ef6\u9577\u3057\u307e\u3057\u305f\u3014\u8ad6\u6587\u5831\u544a\u5024\u3015\u3002<br \/>\n\u30fb\u5168\u751f\u5b58\u671f\u9593\u306e\u4e2d\u592e\u5024\u306f34.9\u304b\u6708 \u5bfe 27.6\u304b\u6708\uff08\u30cf\u30b6\u30fc\u30c9\u6bd4 0.85\u300195%CI 0.68\u301c1.05\u3001\u7247\u5074 p=0.061\uff09\u3067\u3001\u7d71\u8a08\u5b66\u7684\u306b\u6709\u610f\u306a\u5dee\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3014\u8ad6\u6587\u5831\u544a\u5024\u3015\u3002<br \/>\n\u30fbGrade 3\u4ee5\u4e0a\u306e\u6709\u5bb3\u4e8b\u8c61\u306f84% \u5bfe 83%\u3067\u540c\u7a0b\u5ea6\u3001\u6700\u3082\u591a\u304b\u3063\u305f\u306e\u306f\u3069\u3061\u3089\u306e\u7fa4\u3082\u9ad8\u8840\u5727\uff0831% \u5bfe 29%\uff09\u3067\u3057\u305f\u3002\u6cbb\u7642\u306b\u95a2\u9023\u3057\u305f\u6b7b\u4ea1\u306f\u3001\u4f75\u7528\u7fa42\u4f8b\u3001\u30ab\u30dc\u30b6\u30f3\u30c1\u30cb\u30d6\u7fa41\u4f8b\u3067\u3057\u305f\u3014\u8ad6\u6587\u5831\u544a\u5024\u3015\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u81e8\u5e8a\u7684\u610f\u7fa9\uff1a\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306e\u4e00\u3064\uff08\u7121\u5897\u60aa\u751f\u5b58\u671f\u9593\uff09\u306f\u9054\u6210\u3057\u3001\u3082\u3046\u4e00\u3064\uff08\u5168\u751f\u5b58\u671f\u9593\uff09\u306f\u6709\u610f\u5dee\u306b\u5c4a\u304b\u306a\u304b\u3063\u305f\u8a66\u9a13\u3067\u3059\u3002\u8457\u8005\u3089\u306f\u3001\u5168\u751f\u5b58\u671f\u9593\u306b\u6709\u610f\u5dee\u304c\u306a\u304b\u3063\u305f\u3053\u3068\u306b\u89e6\u308c\u305f\u3046\u3048\u3067\u3001\u4f75\u7528\u7642\u6cd5\u306f\u300c\u65b0\u305f\u306a\u6a19\u6e96\u6cbb\u7642\u3068\u306a\u308a\u3046\u308b\uff08might be\uff09\u300d\u3068\u7d50\u8ad6\u3057\u3066\u3044\u307e\u3059\u3002\u304c\u3093\u304c\u9032\u3080\u307e\u3067\u306e\u6642\u9593\u304c\u5ef6\u3073\u308b\u3053\u3068\u306b\u306f\u610f\u5473\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u308c\u304c\u751f\u5b58\u671f\u9593\u306e\u5ef6\u9577\u306b\u307e\u3067\u7d50\u3073\u3064\u304f\u304b\u306f\u5225\u306e\u554f\u3044\u3067\u3059\u3002\u4e8c\u3064\u306e\u8a55\u4fa1\u9805\u76ee\u306e\u7d50\u679c\u3092\u5206\u3051\u3066\u8aad\u3080\u59ff\u52e2\u306f\u3001\u8ad6\u6587\u3092\u8aad\u3080\u3046\u3048\u3067\u5927\u5207\u306b\u3057\u305f\u3044\u7fd2\u6163\u3067\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u51fa\u5178\uff08PubMed \u53ce\u8f09\uff0fPMID: 42586114\uff09\uff1aDOI: 10.1016\/S0140-6736(26)01089-5 <a href=\"https:\/\/www.google.com\/url?q=https:\/\/doi.org\/10.1016\/S0140-6736(26)01089-5&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E\">https:\/\/www.google.com\/url?q=https:\/\/doi.org\/10.1016\/S0140-6736(26)01089-5&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E<\/a> \uff08Motzer RJ, et al. Lancet 2026;408(10557):808-820\uff09<br \/>\n\u95a2\u9023\uff08\u30d9\u30eb\u30ba\u30c1\u30d5\u30a1\u30f3\u3092\u814e\u7d30\u80de\u304c\u3093\u306e\u65e9\u3044\u6bb5\u968e\u304b\u3089\u4f7f\u3046\u8a66\u307f\u3092\u6574\u7406\u3057\u305f\u7dcf\u8aac\uff0fPMID: 42143718\uff09\uff1aDOI: 10.1093\/oncolo\/oyag193 <a href=\"https:\/\/www.google.com\/url?q=https:\/\/doi.org\/10.1093\/oncolo\/oyag193&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E\">https:\/\/www.google.com\/url?q=https:\/\/doi.org\/10.1093\/oncolo\/oyag193&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E<\/a> \uff08Beckermann K. Oncologist 2026;31(7)\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500<\/p>\n<p>\u25a0 \u5b66\u4f1a\u30fb\u30bb\u30df\u30ca\u30fc\uff0f\u884c\u4e8b<\/p>\n<p>&nbsp;<\/p>\n<p>11\/4\uff08\u6c34\uff09\u4ee4\u548c8\u5e74\u5ea6 \u7b2c1\u56de \u7fa4\u99ac\u770c\u304c\u3093\u8a3a\u7642\u9023\u643a\u5354\u8b70\u4f1a\u7814\u4fee\u4f1a\u300c\u3059\u3079\u3066\u306e\u533b\u7642\u8005\u304c\u77e5\u3063\u3066\u304a\u304d\u305f\u3044\u30a2\u30d4\u30a2\u30e9\u30f3\u30b9\u30b1\u30a2\u300d\uff08\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u30fb\u7533\u8fbc\u4e0d\u8981\uff09<br \/>\n\u304c\u3093\u6cbb\u7642\u306b\u4f34\u3046\u8131\u6bdb\u3084\u76ae\u819a\u30fb\u722a\u306e\u5909\u5316\u306a\u3069\u3001\u5916\u898b\u306e\u5909\u5316\u3078\u306e\u652f\u63f4\uff08\u30a2\u30d4\u30a2\u30e9\u30f3\u30b9\u30b1\u30a2\uff09\u3092\u3001\u3053\u306e\u5206\u91ce\u306e\u7b2c\u4e00\u4eba\u8005\u304b\u3089\u5b66\u3079\u308b\u7814\u4fee\u4f1a\u3067\u3059\u3002\u770c\u5185\u306e\u533b\u7642\u8005\u5411\u3051\u306b\u4f01\u753b\u3055\u308c\u305f\u3082\u306e\u3067\u3001\u8077\u7a2e\u3084\u5c02\u9580\u3092\u554f\u308f\u305a\u53d7\u8b1b\u3067\u304d\u307e\u3059\u3002\u533b\u5b66\u751f\u306e\u53c2\u52a0\u53ef\u5426\u3082\u542b\u3081\u3001\u30aa\u30f3\u30e9\u30a4\u30f3\u53c2\u52a0\u306e\u65b9\u6cd5\u306f\u816b\u760d\u5185\u79d1\u307e\u3067\u304a\u554f\u3044\u5408\u308f\u305b\u304f\u3060\u3055\u3044\u3002<br \/>\n\u30fb\u6f14\u984c\uff1a\u6cbb\u7642\u3068\u3068\u3082\u306b\u300c\u305d\u306e\u4eba\u3089\u3057\u3055\u300d\u3092\u652f\u3048\u308b \u301c\u3059\u3079\u3066\u306e\u533b\u7642\u8005\u304c\u77e5\u3063\u3066\u304a\u304d\u305f\u3044\u30a2\u30d4\u30a2\u30e9\u30f3\u30b9\u30b1\u30a2\u301c<br \/>\n\u30fb\u6f14\u8005\uff1a\u85e4\u9593 \u52dd\u5b50 \u5148\u751f\uff08\u56fd\u7acb\u304c\u3093\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u4e2d\u592e\u75c5\u9662 \u30a2\u30d4\u30a2\u30e9\u30f3\u30b9\u652f\u63f4\u30bb\u30f3\u30bf\u30fc\u9577\uff09<br \/>\n\u30fb\u958b\u4f1a\u6328\u62f6\uff1a\u9ad8\u5f35 \u5927\u4eae \u6559\u6388\uff08\u7fa4\u99ac\u5927\u5b66 \u816b\u760d\u5185\u79d1\u5b66\u5206\u91ce\uff0f\u816b\u760d\u30bb\u30f3\u30bf\u30fc\u9577\uff09<br \/>\n\u30fb\u65e5\u6642\uff1a2026\u5e7411\u67084\u65e5\uff08\u6c34\uff0918:00\u301c19:00<br \/>\n\u30fb\u4f1a\u5834\uff1a\u7fa4\u99ac\u5927\u5b66\u533b\u5b66\u90e8 \u81e8\u5e8a\u5927\u5b66\u9662\u8b1b\u5802\uff08\u4f1a\u5834\u53c2\u52a0\uff09\uff0b\u30aa\u30f3\u30e9\u30a4\u30f3\uff08Zoom\uff09\u306e\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u958b\u50ac<br \/>\n\u30fb\u5bfe\u8c61\uff1a\u8077\u7a2e\u30fb\u5c02\u9580\u3092\u554f\u308f\u305a\u3059\u3079\u3066\u306e\u533b\u7642\u5f93\u4e8b\u8005\uff08\u7279\u306b\u304c\u3093\u533b\u7642\u306b\u5f93\u4e8b\u3059\u308b\u533b\u5e2b\uff09\u3002\u7533\u8fbc\u4e0d\u8981<br \/>\n\u30fb\u4e3b\u50ac\uff1a\u7fa4\u99ac\u770c\u304c\u3093\u8a3a\u7642\u9023\u643a\u5354\u8b70\u4f1a<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u6297\u304c\u3093\u85ac\u306e\u526f\u4f5c\u7528\u306f\u3001\u547d\u306b\u95a2\u308f\u308b\u3082\u306e\u3060\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5916\u898b\u306e\u5909\u5316\u306f\u3001\u4ed5\u4e8b\u3084\u4eba\u3068\u306e\u95a2\u308f\u308a\u3092\u7d9a\u3051\u308b\u3046\u3048\u3067\u60a3\u8005\u3055\u3093\u3092\u5927\u304d\u304f\u60a9\u307e\u305b\u307e\u3059\u3002\u85ac\u3092\u9078\u3076\u7acb\u5834\u306e\u816b\u760d\u5185\u79d1\u533b\u3053\u305d\u3001\u77e5\u3063\u3066\u304a\u304d\u305f\u3044\u5206\u91ce\u3067\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>11\/21\uff08\u571f\uff09\u4e2d\u56fd\u30fb\u56db\u56fd\u5730\u533a\u30bb\u30df\u30ca\u30fc\u300111\/22\uff08\u65e5\uff09Best of ESMO 2026\uff08\u524d\u53f7\u304b\u3089\u7d99\u7d9a\uff09<br \/>\n\u5f15\u304d\u7d9a\u304d\u7533\u8fbc\u307f\u3092\u53d7\u3051\u4ed8\u3051\u3066\u3044\u307e\u3059\u3002\u4e2d\u56fd\u30fb\u56db\u56fd\u5730\u533a\u30bb\u30df\u30ca\u30fc\u306f\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u958b\u50ac\u30fb\u53c2\u52a0\u8cbb\u7121\u6599\u30fb\u4f1a\u54e1\u8cc7\u683c\u4e0d\u554f\uff08\u7814\u4fee\u533b\u306e\u53c2\u52a0\u3082\u6b53\u8fce\u3001\u767b\u9332\u7de0\u5207\u306f11\u670816\u65e5\uff09\u3001Best of ESMO 2026 \u306f\u4eca\u5e74\u304b\u3089\u5b66\u751f\u30fb\u521d\u671f\u7814\u4fee\u533b\u304c\u7121\u6599\u3067\u53c2\u52a0\u3067\u304d\u307e\u3059\uff08\u7533\u8fbc\u6642\u306b\u5b66\u751f\u8a3c\u306a\u3069\u306e\u30a2\u30c3\u30d7\u30ed\u30fc\u30c9\u304c\u5fc5\u8981\uff09\u3002<br \/>\n\u30fb\u4e2d\u56fd\u30fb\u56db\u56fd\u5730\u533a\u30bb\u30df\u30ca\u30fc \u53c2\u52a0\u767b\u9332\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/forms.gle\/9gQiBqVmjwhmqHci7&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E\">https:\/\/www.google.com\/url?q=https:\/\/forms.gle\/9gQiBqVmjwhmqHci7&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E<\/a><br \/>\n\u30fbBest of ESMO 2026 \u7533\u8fbc\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/medicalprime.jp\/event\/boe2026\/&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E\">https:\/\/www.google.com\/url?q=https:\/\/medicalprime.jp\/event\/boe2026\/&amp;source=gmail&amp;ust=1791497031072000&amp;sa=E<\/a><br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u4eca\u9031\u306e\u4e00\u5831\u306e\u3088\u3046\u306a\u8a66\u9a13\u7d50\u679c\u306e\u53d7\u3051\u6b62\u3081\u65b9\u3092\u77e5\u308b\u6a5f\u4f1a\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u5f53\u79d1\u306e\u898b\u5b66\u30fb\u5b9f\u7fd2\u30fb\u9032\u8def\u76f8\u8ac7\u306f\u968f\u6642\u53d7\u3051\u4ed8\u3051\u3066\u3044\u307e\u3059<br \/>\n\u5916\u6765\u3084\u30ab\u30f3\u30d5\u30a1\u30ec\u30f3\u30b9\u306e\u898b\u5b66\u3001\u77ed\u671f\u306e\u5b9f\u7fd2\u306a\u3069\u3001\u5e0c\u671b\u306b\u5fdc\u3058\u3066\u65e5\u7a0b\u3092\u8abf\u6574\u3057\u307e\u3059\u3002\u5b66\u5e74\u3084\u6240\u5c5e\u306f\u554f\u3044\u307e\u305b\u3093\u3002\u304a\u554f\u3044\u5408\u308f\u305b\u306f\u816b\u760d\u5185\u79d1\u307e\u3067\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500<\/p>\n<p>\u25a0 \u3072\u3068\u3053\u3068\u30b3\u30e9\u30e0 \u2015 \u814e\u7d30\u80de\u304c\u3093\u3068\u300c\u9178\u7d20\u30bb\u30f3\u30b5\u30fc\u300d<\/p>\n<p>&nbsp;<\/p>\n<p>\u79c1\u305f\u3061\u306e\u7d30\u80de\u306f\u3001\u9178\u7d20\u304c\u8db3\u308a\u306a\u304f\u306a\u308b\u3068\u3001\u305d\u308c\u3092\u611f\u3058\u53d6\u3063\u3066\u4f53\u3092\u9069\u5fdc\u3055\u305b\u308b\u3057\u304f\u307f\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4e2d\u5fc3\u306b\u3044\u308b\u306e\u304c HIF\uff08\u4f4e\u9178\u7d20\u8a98\u5c0e\u56e0\u5b50\uff09\u3068\u3044\u3046\u305f\u3093\u3071\u304f\u8cea\u3067\u3059\u3002\u9178\u7d20\u304c\u8db3\u308a\u306a\u3044\u3068 HIF \u304c\u50cd\u304d\u3001\u8840\u7ba1\u3092\u65b0\u3057\u304f\u4f5c\u3089\u305b\u308b VEGF \u3084\u3001\u8d64\u8840\u7403\u3092\u5897\u3084\u3059\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\u306a\u3069\u306e\u907a\u4f1d\u5b50\u306e\u30b9\u30a4\u30c3\u30c1\u3092\u5165\u308c\u307e\u3059\u3002\u3053\u306e\u3057\u304f\u307f\u306e\u89e3\u660e\u306b\u306f\u30012019\u5e74\u306e\u30ce\u30fc\u30d9\u30eb\u751f\u7406\u5b66\u30fb\u533b\u5b66\u8cde\u304c\u8d08\u3089\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>\u9178\u7d20\u304c\u5341\u5206\u306b\u3042\u308b\u3068\u304d\u3001HIF \u3092\u5206\u89e3\u3078\u5c0e\u304f\u5f79\u76ee\u3092\u62c5\u3063\u3066\u3044\u308b\u306e\u304c VHL \u3068\u3044\u3046\u305f\u3093\u3071\u304f\u8cea\u3067\u3059\u3002\u6de1\u660e\u7d30\u80de\u578b\u306e\u814e\u7d30\u80de\u304c\u3093\u3067\u306f\u3001\u591a\u304f\u306e\u5834\u5408\u3053\u306e VHL \u306e\u907a\u4f1d\u5b50\u304c\u50cd\u304b\u306a\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3059\u308b\u3068\u3001\u9178\u7d20\u304c\u8db3\u308a\u3066\u3044\u3066\u3082 HIF \u304c\u5206\u89e3\u3055\u308c\u305a\u306b\u305f\u307e\u308a\u307e\u3059\u3002\u7d30\u80de\u306f\u300c\u3044\u3064\u3082\u9178\u7d20\u304c\u8db3\u308a\u306a\u3044\u300d\u72b6\u614b\u3068\u53d7\u3051\u53d6\u308a\u3001\u8840\u7ba1\u3092\u4f5c\u3089\u305b\u308b\u4fe1\u53f7\u3092\u51fa\u3057\u7d9a\u3051\u307e\u3059\u3002\u814e\u7d30\u80de\u304c\u3093\u304c\u8840\u7ba1\u306b\u5bcc\u3080\u304c\u3093\u3067\u3042\u308b\u3053\u3068\u3001\u305d\u3057\u3066 VEGF \u306e\u53d7\u5bb9\u4f53\u3092\u6291\u3048\u308b\u85ac\uff08\u30ec\u30f3\u30d0\u30c1\u30cb\u30d6\u3084\u30ab\u30dc\u30b6\u30f3\u30c1\u30cb\u30d6\u306a\u3069\uff09\u304c\u52b9\u679c\u3092\u793a\u3059\u3053\u3068\u306f\u3001\u3053\u306e\u6027\u8cea\u304b\u3089\u8aac\u660e\u3067\u304d\u307e\u3059\u3002<\/p>\n<p>\u30d9\u30eb\u30ba\u30c1\u30d5\u30a1\u30f3\u306f\u3001HIF \u306e\u4ef2\u9593\u306e\u3046\u3061 HIF-2\u03b1 \u306e\u50cd\u304d\u3092\u76f4\u63a5\u6291\u3048\u308b\u85ac\u3067\u3059\u3002VEGF \u53d7\u5bb9\u4f53\u3092\u6291\u3048\u308b\u85ac\u304c\u4fe1\u53f7\u306e\u300c\u4e0b\u6d41\u300d\u3092\u6b62\u3081\u308b\u306e\u306b\u5bfe\u3057\u3066\u3001\u30d9\u30eb\u30ba\u30c1\u30d5\u30a1\u30f3\u306f\u300c\u4e0a\u6d41\u300d\u3067\u6b62\u3081\u308b\u3002\u4eca\u56de\u306e\u4f75\u7528\u306f\u3001\u540c\u3058\u6d41\u308c\u3092\u4e8c\u304b\u6240\u3067\u6291\u3048\u308b\u7d44\u307f\u5408\u308f\u305b\u3068\u8a00\u3048\u307e\u3059\u3002\u526f\u4f5c\u7528\u306b\u8ca7\u8840\u304c\u6319\u304c\u308b\u306e\u306f\u3001HIF-2\u03b1 \u304c\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\u306e\u7523\u751f\u3092\u62c5\u3063\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u8aac\u660e\u3067\u304d\u307e\u3059\u3002\u4f4e\u9178\u7d20\u3082\u3001HIF-2\u03b1 \u304c\u4f53\u306e\u9178\u7d20\u3078\u306e\u9069\u5fdc\u306b\u95a2\u308f\u308b\u3053\u3068\u3068\u95a2\u4fc2\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u526f\u4f5c\u7528\u306e\u4e00\u89a7\u3092\u78ba\u8a8d\u3059\u308b\u306e\u3068\u4e26\u3093\u3067\u3001\u300c\u3053\u306e\u85ac\u306f\u4f53\u306e\u3069\u306e\u3057\u304f\u307f\u306b\u89e6\u308c\u3066\u3044\u308b\u306e\u304b\u300d\u3092\u8003\u3048\u3066\u307f\u308b\u3002\u305d\u3046\u3059\u308b\u3068\u3001\u521d\u3081\u3066\u51fa\u4f1a\u3046\u85ac\u3067\u3082\u3001\u3069\u3093\u306a\u526f\u4f5c\u7528\u306b\u6c17\u3092\u3064\u3051\u308c\u3070\u3088\u3044\u304b\u3001\u3042\u308b\u7a0b\u5ea6\u306e\u898b\u5f53\u304c\u3064\u304f\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002\u57fa\u790e\u533b\u5b66\u3067\u5b66\u3093\u3060\u3053\u3068\u304c\u3001\u305d\u306e\u307e\u307e\u8a3a\u7642\u306b\u3064\u306a\u304c\u308b\u5834\u9762\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500<br \/>\n\u7fa4\u99ac\u5927\u5b66\u533b\u5b66\u90e8\u9644\u5c5e\u75c5\u9662 \u816b\u760d\u5185\u79d1\uff0f2026-10-08 \u4f5c\u6210<br \/>\n\u203b \u63b2\u8f09\u5185\u5bb9\u30fb\u51fa\u5178\u306f\u4f5c\u6210\u6642\u70b9\u306e\u60c5\u5831\u306b\u57fa\u3065\u304d\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4eca\u9031\u306e\u816b\u760d\u5185\u79d1\uff082026\u5e7410\u6708\u7b2c1\u9031\uff0f9\u670828\u65e5\u301c10\u67084\u65e5\uff09 \u7fa4\u99ac\u5927\u5b66\u533b\u5b66\u90e8\u9644\u5c5e\u75c5\u9662 \u816b\u760d\u5185\u79d1 &nbsp; \u816b\u760d\u5185\u79d1\u306b\u95a2\u5fc3\u306e\u3042\u308b\u533b\u5b66\u751f\u30fb\u7814\u4fee\u533b\u306e\u65b9\u3078\u3002\u5f53\u79d1\u306e\u4e00\u9031\u9593\u3068\u3001\u304c\u3093\u85ac\u7269\u7642\u6cd5\u3092\u3081\u3050\u308b\u52d5\u304d\u3092\u6bce\u9031\u304a\u4f1d\u3048\u3057\u307e\u3059\u3002 \u4eca [&hellip;]<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-2752","post","type-post","status-publish","format-standard","hentry","category-information"],"publishpress_future_action":{"enabled":false,"date":"2026-10-15 16:41:16","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/oncoc.showa.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2752","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/oncoc.showa.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/oncoc.showa.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/oncoc.showa.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/oncoc.showa.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2752"}],"version-history":[{"count":8,"href":"https:\/\/oncoc.showa.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2752\/revisions"}],"predecessor-version":[{"id":2760,"href":"https:\/\/oncoc.showa.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2752\/revisions\/2760"}],"wp:attachment":[{"href":"https:\/\/oncoc.showa.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2752"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/oncoc.showa.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2752"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/oncoc.showa.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2752"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}