{"id":2717,"date":"2026-09-24T16:11:04","date_gmt":"2026-09-24T07:11:04","guid":{"rendered":"https:\/\/oncoc.showa.gunma-u.ac.jp\/?p=2717"},"modified":"2026-09-30T17:14:09","modified_gmt":"2026-09-30T08:14:09","slug":"%e3%80%90new%e3%80%91%e4%bb%8a%e9%80%b1%e3%81%ae%e8%85%ab%e7%98%8d%e5%86%85%e7%a7%919-14-9-20","status":"publish","type":"post","link":"https:\/\/oncoc.showa.gunma-u.ac.jp\/?p=2717","title":{"rendered":"\u4eca\u9031\u306e\u816b\u760d\u5185\u79d1(9\/14-9\/20)"},"content":{"rendered":"<p>\u4eca\u9031\u306e\u816b\u760d\u5185\u79d1\uff082026\u5e749\u6708\u7b2c3\u9031\uff0f9\u670814\u65e5\u301c9\u670820\u65e5\uff09<br \/>\n\u7fa4\u99ac\u5927\u5b66\u533b\u5b66\u90e8\u9644\u5c5e\u75c5\u9662 \u816b\u760d\u5185\u79d1<\/p>\n<p>&nbsp;<\/p>\n<p>\u816b\u760d\u5185\u79d1\u306b\u95a2\u5fc3\u306e\u3042\u308b\u533b\u5b66\u751f\u30fb\u7814\u4fee\u533b\u306e\u65b9\u3078\u3002\u5f53\u79d1\u306e\u4e00\u9031\u9593\u306e\u6d3b\u52d5\u3068\u3001\u304c\u3093\u85ac\u7269\u7642\u6cd5\u3092\u3081\u3050\u308b\u4e16\u306e\u4e2d\u306e\u52d5\u304d\uff08\u8ad6\u6587\u30fb\u5b66\u4f1a\u30fb\u5236\u5ea6\uff09\u3092\u3001\u6bce\u9031\u307e\u3068\u3081\u3066\u304a\u4f1d\u3048\u3057\u307e\u3059\u3002<\/p>\n<p>\u4eca\u9031\u306e\u5f53\u79d1\u306f\u3001\u533b\u5b66\u79d14\u5e74\u751f\u306b\u5411\u3051\u305f\u7279\u5225\u8b1b\u6f14\u304b\u3089\u59cb\u307e\u308a\u3001\u533b\u7642\u5b89\u5168\u9031\u9593\u306e\u884c\u4e8b\u3084\u59d4\u54e1\u4f1a\u306a\u3069\u3001\u75c5\u9662\u5168\u4f53\u3067\u52d5\u304f\u4ed5\u4e8b\u306e\u591a\u3044\u4e00\u9031\u9593\u3067\u3057\u305f\u3002\u4e16\u306e\u4e2d\u306e\u52d5\u304d\u3068\u3057\u3066\u306f\u30019\u670816\u65e5\u306b\u4e73\u304c\u3093\u306e\u4e00\u6b21\u6cbb\u7642\u30672\u3064\u306e\u6297\u4f53\u85ac\u7269\u8907\u5408\u4f53\uff08ADC\uff09\u304c\u627f\u8a8d\u3055\u308c\u305f\u8a71\u984c\u3092\u53d6\u308a\u4e0a\u3052\u307e\u3059\u3002\u524d\u53f7\u306e\u5375\u5de3\u304c\u3093\u306b\u7d9a\u304d\u3001ADC \u304c\u6cbb\u7642\u306e\u65e9\u3044\u6bb5\u968e\u306b\u5165\u3063\u3066\u304d\u3066\u3044\u308b\u6d41\u308c\u3092\u3001\u6839\u62e0\u3068\u306a\u3063\u305f\u8a66\u9a13\u3068\u4e00\u7dd2\u306b\u898b\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500<br \/>\n\u25a0 \u4eca\u9031\u306e\u5f53\u79d1\u304b\u3089<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u533b\u5b66\u79d14\u5e74\u751f\u3078\u306e\u7279\u5225\u8b1b\u6f14\uff08\u304c\u3093\u7814\u6709\u660e\u75c5\u9662 \u9ad8\u91ce\u5229\u5b9f\u5148\u751f\uff09<br \/>\n\u81e8\u5e8a\u5b9f\u7fd2\u5165\u9580\u306e\u6388\u696d\u306e\u4e00\u30b3\u30de\u3068\u3057\u3066\u3001\u304c\u3093\u7814\u6709\u660e\u75c5\u9662\u306e\u9ad8\u91ce\u5229\u5b9f\u5148\u751f\u3092\u304a\u62db\u304d\u3057\u3001\u300c\u816b\u760d\u5185\u79d1\u306e\u672a\u6765\u3092\u5275\u308b\u306e\u306f\u541b\u3060\uff01\u300d\u3068\u984c\u3057\u305f\u7279\u5225\u8b1b\u6f14\u3092\u3057\u3066\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u3002\u816b\u760d\u5185\u79d1\u3068\u3044\u3046\u4ed5\u4e8b\u306e\u4e2d\u8eab\u3084\u3001\u3053\u308c\u304b\u3089\u306e\u816b\u760d\u5185\u79d1\u306b\u6c42\u3081\u3089\u308c\u308b\u5f79\u5272\u306b\u3064\u3044\u3066\u3001\u3054\u81ea\u8eab\u306e\u7d4c\u9a13\u3092\u4ea4\u3048\u3066\u304a\u8a71\u3057\u3044\u305f\u3060\u3044\u3066\u3044\u307e\u3059\u3002\u8b1b\u6f14\u306e\u3042\u3068\u306b\u306f\u3001\u5b66\u5e74\u3092\u554f\u308f\u305a\u53c2\u52a0\u3067\u304d\u308b\u76f8\u8ac7\u4f1a\u306e\u6642\u9593\u3082\u8a2d\u3051\u307e\u3057\u305f\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u81e8\u5e8a\u5b9f\u7fd2\u304c\u59cb\u307e\u308b\u524d\u306e\u6642\u671f\u306b\u3001\u7b2c\u4e00\u7dda\u306e\u816b\u760d\u5185\u79d1\u533b\u306e\u8a71\u3092\u76f4\u63a5\u805e\u3051\u308b\u306e\u306f\u8cb4\u91cd\u306a\u6a5f\u4f1a\u3067\u3059\u3002\u300c\u4f55\u306e\u75c5\u6c17\u3092\u8a3a\u308b\u304b\u300d\u3060\u3051\u3067\u306a\u304f\u300c\u60a3\u8005\u3055\u3093\u3068\u3069\u3046\u5411\u304d\u5408\u3046\u304b\u300d\u3068\u3044\u3046\u8996\u70b9\u3067\u9032\u8def\u3092\u8003\u3048\u308b\u304d\u3063\u304b\u3051\u306b\u306a\u308c\u3070\u3001\u3068\u8003\u3048\u3066\u4f01\u753b\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u30fb\u5916\u6765\u5316\u5b66\u7642\u6cd5\u30bb\u30f3\u30bf\u30fc\u306e\u904b\u55b6\u59d4\u54e1\u4f1a<br \/>\n\u6bce\u6708\u306e\u5b9a\u4f8b\u306e\u59d4\u54e1\u4f1a\u3067\u3001\u5916\u6765\u5316\u5b66\u7642\u6cd5\u30bb\u30f3\u30bf\u30fc\u306e\u5229\u7528\u72b6\u6cc1\u3084\u3001\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\u306e\u4f7f\u7528\u72b6\u6cc1\u306e\u5831\u544a\u304c\u3042\u308a\u307e\u3057\u305f\u3002\u3042\u308f\u305b\u3066\u3001\u9023\u4f11\u4e2d\u306e\u5916\u6765\u5316\u5b66\u7642\u6cd5\u306e\u53d7\u3051\u5165\u308c\u4f53\u5236\u3084\u3001\u65b0\u3057\u3044\u6cbb\u7642\u30ec\u30b8\u30e1\u30f3\u3067\u4f7f\u3046\u643a\u5e2f\u578b\u306e\u6301\u7d9a\u6ce8\u5165\u30dd\u30f3\u30d7\u306e\u6271\u3044\u306b\u3064\u3044\u3066\u3082\u8a71\u3057\u5408\u3044\u307e\u3057\u305f\u3002\u533b\u5e2b\u306e\u307b\u304b\u3001\u770b\u8b77\u5e2b\u30fb\u85ac\u5264\u5e2b\u30fb\u4e8b\u52d9\u306e\u62c5\u5f53\u8005\u304c\u53c2\u52a0\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u5916\u6765\u3067\u6297\u304c\u3093\u85ac\u306e\u6cbb\u7642\u3092\u7d9a\u3051\u308b\u306b\u306f\u3001\u85ac\u305d\u306e\u3082\u306e\u3060\u3051\u3067\u306a\u304f\u3001\u9023\u4f11\u306e\u3068\u304d\u306e\u4f53\u5236\u3084\u3001\u81ea\u5b85\u3067\u85ac\u3092\u6d41\u3057\u7d9a\u3051\u308b\u5668\u5177\u306e\u7ba1\u7406\u3068\u3044\u3063\u305f\u300c\u6cbb\u7642\u3092\u652f\u3048\u308b\u4ed5\u7d44\u307f\u300d\u304c\u6b20\u304b\u305b\u307e\u305b\u3093\u3002\u3053\u3046\u3057\u305f\u8a71\u3057\u5408\u3044\u306f\u8868\u306b\u51fa\u306b\u304f\u3044\u306e\u3067\u3059\u304c\u3001\u816b\u760d\u5185\u79d1\u306e\u65e5\u5e38\u306e\u5927\u5207\u306a\u4e00\u90e8\u3067\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u533b\u7642\u5b89\u5168\u9031\u9593 \u2015 \u8a93\u3044\u306e\u3064\u3069\u3044\u3068\u533b\u7642\u5b89\u5168\u8b1b\u6f14\u4f1a<br \/>\n9\u670814\u65e5\u304b\u308918\u65e5\u306f\u75c5\u9662\u306e\u533b\u7642\u5b89\u5168\u9031\u9593\u3067\u3057\u305f\u3002\u521d\u65e5\u306b\u306f\u3001\u533b\u7642\u5b89\u5168\u3078\u306e\u8a93\u3044\u3092\u65b0\u305f\u306b\u3059\u308b\u5f0f\u5178\u300c\u8a93\u3044\u306e\u3064\u3069\u3044\u300d\u304c\u958b\u304b\u308c\u3001\u9031\u306e\u5f8c\u534a\u306b\u306f\u75c5\u9662\u8077\u54e1\u5411\u3051\u306e\u533b\u7642\u5b89\u5168\u8b1b\u6f14\u4f1a\u304c\u3042\u308a\u307e\u3057\u305f\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u6297\u304c\u3093\u85ac\u306f\u3001\u91cf\u3084\u6295\u4e0e\u306e\u9806\u756a\u3092\u5c11\u3057\u9593\u9055\u3048\u308b\u3060\u3051\u3067\u5927\u304d\u306a\u5bb3\u306b\u3064\u306a\u304c\u308b\u85ac\u3067\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u304c\u3093\u85ac\u7269\u7642\u6cd5\u306f\u533b\u7642\u5b89\u5168\u3068\u5207\u308a\u96e2\u305b\u307e\u305b\u3093\u3002\u6bce\u5e74\u3053\u306e\u6642\u671f\u306b\u3001\u75c5\u9662\u5168\u4f53\u3067\u57fa\u672c\u3092\u78ba\u304b\u3081\u76f4\u3059\u6a5f\u4f1a\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u533b\u5b66\u751f\u304c\u307e\u3068\u3081\u305f\u7814\u7a76\u8ad6\u6587\u306e\u63a8\u6572<br \/>\n\u5f53\u79d1\u3067\u7814\u7a76\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u308b\u533b\u5b66\u751f\u304c\u3001\u30a2\u30f3\u30b1\u30fc\u30c8\u8abf\u67fb\u306e\u7d50\u679c\u3092\u8ad6\u6587\u539f\u7a3f\u306b\u307e\u3068\u3081\u3001\u6307\u5c0e\u533b\u306e\u6dfb\u524a\u3092\u7d4c\u3066\u6559\u6388\u306b\u63d0\u51fa\u3057\u307e\u3057\u305f\u3002\u6559\u6388\u304b\u3089\u306f\u3001\u7d50\u679c\u306e\u4e2d\u3067\u4f55\u3092\u4e2d\u5fc3\u306b\u636e\u3048\u308b\u304b\u3001\u3069\u3053\u307e\u3067\u3092\u63a2\u7d22\u7684\u306a\u89e3\u6790\u3068\u3057\u3066\u63a7\u3048\u3081\u306b\u66f8\u304f\u304b\u3001\u3068\u3044\u3063\u305f\u30b3\u30e1\u30f3\u30c8\u304c\u8fd4\u3055\u308c\u3001\u5b66\u751f\u304c\u4fee\u6b63\u65b9\u91dd\u3092\u8fd4\u4fe1\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u8ad6\u6587\u306f\u3001\u66f8\u3044\u3066\u304b\u3089\u306e\u76f4\u3057\u304c\u672c\u756a\u3067\u3059\u3002\u6307\u6458\u3092\u53d7\u3051\u3066\u300c\u3069\u3046\u76f4\u3059\u304b\u300d\u3092\u81ea\u5206\u306e\u8a00\u8449\u3067\u8fd4\u3059\u3084\u308a\u3068\u308a\u306e\u4e2d\u3067\u3001\u30c7\u30fc\u30bf\u304b\u3089\u8a00\u3048\u308b\u3053\u3068\u3068\u8a00\u3048\u306a\u3044\u3053\u3068\u306e\u7dda\u5f15\u304d\u304c\u8eab\u306b\u3064\u3044\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u81e8\u5e8a\u7814\u4fee\u306e\u904b\u55b6\u306b\u95a2\u308f\u308b\u4f1a\u8b70<br \/>\n\u521d\u671f\u7814\u4fee\u306e\u904b\u55b6\u3092\u8a71\u3057\u5408\u3046\u4f1a\u8b70\u304c\u30aa\u30f3\u30e9\u30a4\u30f3\u3067\u958b\u304b\u308c\u3001\u5f53\u79d1\u3082\u59d4\u54e1\u3068\u3057\u3066\u53c2\u52a0\u3057\u307e\u3057\u305f\u3002\u5192\u982d\u3067\u306f\u3001\u7814\u4fee\u533b\u306e\u75c7\u4f8b\u767a\u8868\u4f1a\u306e\u8868\u5f70\u3082\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u5f53\u79d1\u306f\u7814\u4fee\u533b\u306e\u30ed\u30fc\u30c6\u30fc\u30b7\u30e7\u30f3\u3092\u53d7\u3051\u5165\u308c\u3066\u3044\u307e\u3059\u3002\u7814\u4fee\u306e\u4ed5\u7d44\u307f\u3065\u304f\u308a\u306b\u95a2\u308f\u308b\u7acb\u5834\u304b\u3089\u3082\u3001\u7814\u4fee\u533b\u306e\u65b9\u304c\u816b\u760d\u5185\u79d1\u3067\u5b66\u3073\u3084\u3059\u3044\u74b0\u5883\u3092\u6574\u3048\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n<p>\u203b \u500b\u3005\u306e\u60a3\u8005\u3055\u3093\u30fb\u75c7\u4f8b\u306b\u95a2\u3059\u308b\u60c5\u5831\u306f\u542b\u307f\u307e\u305b\u3093\u3002\u5f53\u79d1\u306e\u6d3b\u52d5\u3092\u4e00\u822c\u5316\u3057\u3066\u3054\u7d39\u4ecb\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500<br \/>\n\u25a0 \u4eca\u9031\u306e\u816b\u760d\u5185\u79d1\u30cb\u30e5\u30fc\u30b9<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u30c0\u30c8\u30ed\u30a6\u30a7\u30a4\u70b9\u6ef4\u9759\u6ce8\u7528100mg\uff08\u30c0\u30c8\u30dd\u30bf\u30de\u30d6 \u30c7\u30eb\u30af\u30b9\u30c6\u30ab\u30f3\uff09\u3001\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306b\u52b9\u80fd\u8ffd\u52a0\uff08\u6839\u62e0\u306f\u4e00\u6b21\u6cbb\u7642\u306e\u7b2c\u2162\u76f8\u8a66\u9a13\uff09\u3014\u85ac\u4e8b\u627f\u8a8d\u3015<br \/>\n2026\u5e749\u670816\u65e5\u3001\u30c0\u30c8\u30dd\u30bf\u30de\u30d6 \u30c7\u30eb\u30af\u30b9\u30c6\u30ab\u30f3\uff08\u8ca9\u58f2\u540d\uff1a\u30c0\u30c8\u30ed\u30a6\u30a7\u30a4\u70b9\u6ef4\u9759\u6ce8\u7528100mg\uff09\u304c\u3001\u300c\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u9670\u6027\u304b\u3064HER2\u9670\u6027\u306e\u624b\u8853\u4e0d\u80fd\u53c8\u306f\u518d\u767a\u4e73\u764c\u300d\u3001\u3044\u308f\u3086\u308b\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306b\u3064\u3044\u3066\u3001\u88fd\u9020\u8ca9\u58f2\u627f\u8a8d\u4e8b\u9805\u306e\u4e00\u90e8\u5909\u66f4\u627f\u8a8d\uff08\u65b0\u52b9\u80fd\u30fb\u65b0\u7528\u91cf\uff09\u3092\u53d7\u3051\u307e\u3057\u305f\u3002\u512a\u5148\u5be9\u67fb\u306e\u5bfe\u8c61\u3068\u306a\u3063\u3066\u3044\u305f\u54c1\u76ee\u3067\u3059\u3002<br \/>\n\u3053\u306e\u85ac\u306f\u3001\u304c\u3093\u7d30\u80de\u306e\u8868\u9762\u306b\u591a\u304f\u51fa\u3066\u3044\u308b TROP-2 \u3068\u3044\u3046\u305f\u3093\u3071\u304f\u8cea\u306b\u7d50\u5408\u3059\u308b\u6297\u4f53\u306b\u3001\u30c8\u30dd\u30a4\u30bd\u30e1\u30e9\u30fc\u30bc\u2160\u963b\u5bb3\u85ac\uff08DXd\uff09\u3092\u3064\u306a\u3044\u3060\u6297\u4f53\u85ac\u7269\u8907\u5408\u4f53\uff08ADC\uff09\u3067\u3059\u3002\u6297\u4f53\u306f\u672d\u5e4c\u533b\u79d1\u5927\u5b66\u3068\u306e\u5171\u540c\u7814\u7a76\u304b\u3089\u751f\u307e\u308c\u305f\u3082\u306e\u3067\u30012024\u5e7412\u6708\u306b\u65e5\u672c\u3067\u3001\u5316\u5b66\u7642\u6cd5\u6b74\u306e\u3042\u308b\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\u304b\u3064HER2\u9670\u6027\u306e\u624b\u8853\u4e0d\u80fd\u53c8\u306f\u518d\u767a\u4e73\u764c\u3092\u5bfe\u8c61\u306b\u3001\u4e16\u754c\u3067\u521d\u3081\u3066\u627f\u8a8d\u3055\u308c\u305f\u85ac\u3067\u3059\u3002\u4eca\u56de\u306e\u627f\u8a8d\u306f\u3001\u514d\u75ab\u7642\u6cd5\u306e\u5bfe\u8c61\u3068\u306a\u3089\u306a\u3044\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306e\u4e00\u6b21\u6cbb\u7642\u3092\u5bfe\u8c61\u306b\u3057\u305f\u56fd\u969b\u7b2c\u2162\u76f8\u8a66\u9a13 TROPION-Breast02 \u306e\u7d50\u679c\u306b\u57fa\u3065\u3044\u3066\u3044\u307e\u3059\u3002\u88fd\u9020\u8ca9\u58f2\u5143\u306b\u3088\u308b\u3068\u3001\u8ee2\u79fb\u6027\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306e\u7d0470%\u306f\u514d\u75ab\u7642\u6cd5\u306e\u5bfe\u8c61\u3068\u306a\u3089\u305a\u3001\u3053\u308c\u307e\u3067\u306f\u5316\u5b66\u7642\u6cd5\u304c\u6a19\u6e96\u7684\u306a\u4e00\u6b21\u6cbb\u7642\u3068\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3014\u4f01\u696d\u767a\u8868\u5024\u3015\u3002<br \/>\n\u6bb5\u968e\u306b\u3064\u3044\u3066\u306e\u88dc\u8db3\u3067\u3059\u3002\u30c0\u30c8\u30ed\u30a6\u30a7\u30a4\u306f\u3059\u3067\u306b\u85ac\u4fa1\u57fa\u6e96\u306b\u53ce\u8f09\u3055\u308c\u3066\u3044\u308b\u88fd\u54c1\u3067\u3001\u4eca\u56de\u306f\u305d\u306e\u52b9\u80fd\u8ffd\u52a0\u306e\u627f\u8a8d\u3067\u3059\u3002\u306a\u304a\u3001\u627f\u8a8d\u3055\u308c\u305f\u52b9\u80fd\u30fb\u52b9\u679c\u306e\u6587\u8a00\u306b\u306f\u3001\u6cbb\u7642\u306e\u9806\u756a\u3084 PD-L1 \u306e\u6761\u4ef6\u306f\u66f8\u304b\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u5b9f\u969b\u306b\u3069\u306e\u60a3\u8005\u3055\u3093\u306b\u4f7f\u3046\u304b\u306f\u3001\u6dfb\u4ed8\u6587\u66f8\u306a\u3069\u3067\u78ba\u304b\u3081\u307e\u3059\u3002\u7b2c8\u53f7\u3067\u306f\u3001\u85ac\u4e8b\u5be9\u8b70\u4f1a\u306e\u90e8\u4f1a\u306b\u5831\u544a\u3055\u308c\u305f\u54c1\u76ee\u3068\u3057\u3066\u540d\u524d\u3060\u3051\u3092\u304a\u4f1d\u3048\u3057\u3066\u3044\u307e\u3057\u305f\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306f\u3001\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u3084\u6297HER2\u7642\u6cd5\u3068\u3044\u3046\u300c\u72d9\u3044\u3092\u5b9a\u3081\u305f\u6cbb\u7642\u300d\u304c\u4f7f\u3048\u306a\u3044\u304c\u3093\u3067\u3059\u3002\u305d\u3053\u306b\u3001\u5225\u306e\u76ee\u5370\uff08TROP-2\uff09\u3092\u72d9\u3046\u85ac\u304c\u4e00\u6b21\u6cbb\u7642\u304b\u3089\u5165\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u6cbb\u7642\u306e\u9078\u629e\u80a2\u306f\u3001\u300c\u3069\u306e\u76ee\u5370\u3092\u6301\u3063\u3066\u3044\u308b\u304b\u300d\u3067\u5e83\u304c\u3063\u3066\u3044\u304d\u307e\u3059\u3002\u6839\u62e0\u3068\u306a\u3063\u305f\u8a66\u9a13\u306f\u3001\u4e0b\u306e\u300c\u4eca\u9031\u306e\u4e00\u5831\u300d\u3067\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n<p>\u51fa\u5178\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.daiichisankyo.co.jp\/files\/news\/pressrelease\/pdf\/202609\/20260916_J.pdf&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\" target=\"_blank\" rel=\"noopener\">\u7b2c\u4e00\u4e09\u5171\u682a\u5f0f\u4f1a\u793e\u300c\u6297\u60aa\u6027\u816b\u760d\u5264\u300c\u30a8\u30f3\u30cf\u30fc\u30c4\u00ae\u300d\u3068\u300c\u30c0\u30c8\u30ed\u30a6\u30a7\u30a4\u00ae\u300d\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u8ee2\u79fb\u6027\u4e73\u304c\u3093\u4e00\u6b21\u6cbb\u7642\u306b\u4fc2\u308b\uff12\u3064\u306e\u4e00\u90e8\u5909\u66f4\u627f\u8a8d\u53d6\u5f97\u306e\u304a\u77e5\u3089\u305b\u300d\uff082026\u5e749\u670816\u65e5\uff09<\/a> \uff0f<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.pmda.go.jp\/review-services\/drug-reviews\/review-information\/p-drugs\/0040.html&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\" target=\"_blank\" rel=\"noopener\"> PMDA\u300c\u627f\u8a8d\u54c1\u76ee\u4e00\u89a7\uff08\u65b0\u533b\u85ac\u54c1\uff1a2026\u5e749\u6708\uff09\u300d<\/a> \uff0f <a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.daiichisankyo.co.jp\/files\/news\/pressrelease\/pdf\/202412\/20241227_J.pdf&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\" target=\"_blank\" rel=\"noopener\">\u7b2c\u4e00\u4e09\u5171\u682a\u5f0f\u4f1a\u793e\u300c\u6297\u60aa\u6027\u816b\u760d\u5264\u300c\u30c0\u30c8\u30ed\u30a6\u30a7\u30a4\u00ae\u300d\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u88fd\u9020\u8ca9\u58f2\u627f\u8a8d\u53d6\u5f97\u306e\u304a\u77e5\u3089\u305b\u300d\uff082024\u5e7412\u670827\u65e5\uff09\u00a0<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u540c\u3058\u65e5\u306b\u3001HER2\u967d\u6027\u4e73\u304c\u3093\u3067\u3082\u30a8\u30f3\u30cf\u30fc\u30c4\uff08\u30c8\u30e9\u30b9\u30c4\u30ba\u30de\u30d6 \u30c7\u30eb\u30af\u30b9\u30c6\u30ab\u30f3\uff09\u304c\u4e00\u6b21\u6cbb\u7642\u306b\u3014\u85ac\u4e8b\u627f\u8a8d\u3015<br \/>\n\u540c\u30589\u670816\u65e5\u3001\u30c8\u30e9\u30b9\u30c4\u30ba\u30de\u30d6 \u30c7\u30eb\u30af\u30b9\u30c6\u30ab\u30f3\uff08\u8ca9\u58f2\u540d\uff1a\u30a8\u30f3\u30cf\u30fc\u30c4\u70b9\u6ef4\u9759\u6ce8\u7528100mg\uff09\u306b\u3064\u3044\u3066\u3082\u3001\u30da\u30eb\u30c4\u30ba\u30de\u30d6\u3068\u306e\u4f75\u7528\u7642\u6cd5\u3067\u300cHER2\u967d\u6027\u306e\u624b\u8853\u4e0d\u80fd\u53c8\u306f\u518d\u767a\u4e73\u764c\u300d\u306b\u5bfe\u3059\u308b\u4e00\u90e8\u5909\u66f4\u627f\u8a8d\uff08\u65b0\u52b9\u80fd\u30fb\u65b0\u7528\u91cf\uff09\u304c\u51fa\u307e\u3057\u305f\u3002\u6839\u62e0\u306f\u3001HER2\u967d\u6027\u8ee2\u79fb\u6027\u4e73\u304c\u3093\u306e\u4e00\u6b21\u6cbb\u7642\u3092\u5bfe\u8c61\u306b\u3057\u305f\u56fd\u969b\u7b2c\u2162\u76f8\u8a66\u9a13 DESTINY-Breast09 \u3067\u3059\u3002<br \/>\n\u540c\u8a66\u9a13\u306e\u4e2d\u9593\u89e3\u6790\u3067\u306f\u3001\u30a8\u30f3\u30cf\u30fc\u30c4\uff0b\u30da\u30eb\u30c4\u30ba\u30de\u30d6\u7fa4\uff08383\u4f8b\uff09\u3068\u3001\u3053\u308c\u307e\u3067\u306e\u6a19\u6e96\u3060\u3063\u305f\u30bf\u30ad\u30b5\u30f3\u7cfb\u6297\u304c\u3093\u85ac\uff0b\u30c8\u30e9\u30b9\u30c4\u30ba\u30de\u30d6\uff0b\u30da\u30eb\u30c4\u30ba\u30de\u30d6\u7fa4\uff08387\u4f8b\uff09\u3092\u6bd4\u3079\u3001\u7121\u5897\u60aa\u751f\u5b58\u671f\u9593\u306e\u4e2d\u592e\u5024\u306f40.7\u304b\u6708\u5bfe26.9\u304b\u6708\uff08\u30cf\u30b6\u30fc\u30c9\u6bd40.56\u300195%CI 0.44\u301c0.71\uff09\u3067\u3057\u305f\u3002\u4e00\u65b9\u3001\u85ac\u5264\u306b\u95a2\u9023\u3059\u308b\u3068\u5224\u5b9a\u3055\u308c\u305f\u9593\u8cea\u6027\u80ba\u75be\u60a3\u30fb\u80ba\u81d3\u708e\u304c\u3001\u30a8\u30f3\u30cf\u30fc\u30c4\uff0b\u30da\u30eb\u30c4\u30ba\u30de\u30d6\u7fa4\u306712.1%\uff08\u3046\u30612\u4f8b\u306f\u6b7b\u4ea1\uff09\u3001\u5bfe\u7167\u7fa4\u30671.0%\uff08\u3044\u305a\u308c\u3082 Grade 1\u301c2\uff09\u306b\u307f\u3089\u308c\u3066\u3044\u307e\u3059\u3014\u8ad6\u6587\u5831\u544a\u5024\u3015\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u540c\u3058\u65e5\u306b\u3001HER2\u967d\u6027\u3068\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u3068\u3044\u3046\u6027\u8cea\u306e\u7570\u306a\u308b\u4e73\u304c\u3093\u3067\u3001ADC \u304c\u4e00\u6b21\u6cbb\u7642\u306b\u5165\u308a\u307e\u3057\u305f\u3002\u52b9\u679c\u304c\u5927\u304d\u3044\u85ac\u307b\u3069\u3001\u80ba\u306e\u526f\u4f5c\u7528\u306e\u3088\u3046\u306b\u300c\u65e9\u304f\u6c17\u3065\u3044\u3066\u6b62\u3081\u308b\u300d\u305f\u3081\u306e\u5099\u3048\u304c\u5927\u5207\u306b\u306a\u308a\u307e\u3059\u3002<br \/>\n\u51fa\u5178\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.daiichisankyo.co.jp\/files\/news\/pressrelease\/pdf\/202609\/20260916_J.pdf&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\" target=\"_blank\" rel=\"noopener\">\u4e0a\u8a18\u306e\u7b2c\u4e00\u4e09\u5171\u682a\u5f0f\u4f1a\u793e\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9 <\/a>\uff082026\u5e749\u670816\u65e5\uff09<br \/>\n\u8ad6\u6587\uff08PubMed \u53ce\u8f09\uff0fPMID: 41160818\uff09\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/doi.org\/10.1056\/NEJMoa2508668&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\" target=\"_blank\" rel=\"noopener\">DOI: 10.1056\/NEJMoa2508668<\/a>\uff08Tolaney SM, et al. N Engl J Med 2026;394(6):551-562\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb9\u670816\u65e5\u306e\u627f\u8a8d\u306b\u306f\u3001\u307b\u304b\u306b\u3082\u816b\u760d\u9818\u57df\u306e\u54c1\u76ee\u304c\u4e26\u3073\u307e\u3057\u305f\u3014\u85ac\u4e8b\u627f\u8a8d\u3015<br \/>\nPMDA \u306e\u627f\u8a8d\u54c1\u76ee\u4e00\u89a7\uff082026\u5e749\u6708\uff09\u3067\u306f\u3001\u524d\u53f7\u3067\u7d39\u4ecb\u3057\u305f\u5375\u5de3\u304c\u3093\u30fb\u4f4e\u60aa\u6027\u5ea6\u795e\u7d4c\u81a0\u816b\u306e\u85ac\u306e\u307b\u304b\u306b\u3001\u6b21\u306e\u3088\u3046\u306a\u54c1\u76ee\u304c\u6319\u304c\u3063\u3066\u3044\u307e\u3059\u3002<br \/>\n\u30fb\u30ad\u30a4\u30b8\u30a7\u30af\u30c8\u914d\u5408\u76ae\u4e0b\u6ce8395mg\uff0f790mg\uff08\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\uff0f\u30d9\u30e9\u30d2\u30a2\u30eb\u30ed\u30cb\u30c0\u30fc\u30bc \u30a2\u30eb\u30d5\u30a1\uff09\uff1a\u7b2c8\u53f7\u3067\u85ac\u4e8b\u5be9\u8b70\u4f1a\u306e\u90e8\u4f1a\u3067\u306e\u5be9\u8b70\u3092\u304a\u4f1d\u3048\u3057\u305f\u76ae\u4e0b\u6ce8\u88fd\u5264\u304c\u627f\u8a8d\u3055\u308c\u307e\u3057\u305f<br \/>\n\u30fb\u30e2\u30c7\u30fc\u30bd\u30ab\u30d7\u30bb\u30eb125mg\uff08\u30c9\u30eb\u30c0\u30d3\u30d7\u30ed\u30f3\u5869\u9178\u5869\uff09\uff1a\u3073\u307e\u3093\u6027\u6b63\u4e2d\u81a0\u816b\uff08\u65b0\u6709\u52b9\u6210\u5206\u30fb\u5e0c\u5c11\u75be\u75c5\u7528\u533b\u85ac\u54c1\uff09<br \/>\n\u30fb\u30a4\u30d6\u30e9\u30f3\u30b9\u9320\uff08\u30d1\u30eb\u30dc\u30b7\u30af\u30ea\u30d6\uff09\uff1a\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\u304b\u3064HER2\u967d\u6027\u306e\u624b\u8853\u4e0d\u80fd\u53c8\u306f\u518d\u767a\u4e73\u764c\u306b\u304a\u3051\u308b\u3001\u5316\u5b66\u7642\u6cd5\u5f8c\u306e\u7dad\u6301\u7642\u6cd5\uff08\u52b9\u80fd\u8ffd\u52a0\uff09<br \/>\n\u30fb\u30ea\u30d6\u30ed\u30d5\u30a1\u30ba\u914d\u5408\u76ae\u4e0b\u6ce8\uff08\u30a2\u30df\u30d0\u30f3\u30bf\u30de\u30d6\uff0f\u30dc\u30eb\u30d2\u30a2\u30eb\u30ed\u30cb\u30c0\u30fc\u30bc \u30a2\u30eb\u30d5\u30a1\uff09\uff1aEGFR\u907a\u4f1d\u5b50\u30a8\u30af\u30bd\u30f320\u633f\u5165\u5909\u7570\u967d\u6027\u3001\u304a\u3088\u3073EGFR\u907a\u4f1d\u5b50\u5909\u7570\u967d\u6027\u306e\u5207\u9664\u4e0d\u80fd\u306a\u9032\u884c\u30fb\u518d\u767a\u306e\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08\u76ae\u4e0b\u6ce8\u306e\u914d\u5408\u5264\u3002\u65b0\u7528\u91cf\u30fb\u5264\u5f62\u8ffd\u52a0\uff09<br \/>\n\u30fb\u30c6\u30d3\u30e0\u30d6\u30e9\u70b9\u6ef4\u9759\u6ce8100mg\uff08\u30c1\u30b9\u30ec\u30ea\u30ba\u30de\u30d6\uff09\uff1a\u518d\u767a\u53c8\u306f\u9060\u9694\u8ee2\u79fb\u3092\u6709\u3059\u308b\u4e0a\u54bd\u982d\u764c\uff08\u6761\u4ef6\u4ed8\u304d\u627f\u8a8d\u30fb\u52b9\u80fd\u8ffd\u52a0\uff09<br \/>\n\u3053\u306e\u307b\u304b\u3001\u8840\u6db2\u304c\u3093\u306e\u9818\u57df\u3067\u3082\u30a8\u30d7\u30ad\u30f3\u30ea\u76ae\u4e0b\u6ce8\uff08\u30a8\u30d7\u30b3\u30ea\u30bf\u30de\u30d6\uff09\u3001\u30c6\u30af\u30d9\u30a4\u30ea\u76ae\u4e0b\u6ce8\uff08\u30c6\u30af\u30ea\u30b9\u30bf\u30de\u30d6\uff09\u306e\u7528\u91cf\u3084\u52b9\u80fd\u306e\u8ffd\u52a0\u304c\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u4e00\u89a7\u3092\u898b\u308b\u3068\u30011\u56de\u306e\u627f\u8a8d\u3067\u3053\u308c\u3060\u3051\u306e\u54c1\u76ee\u304c\u4e26\u3076\u3053\u3068\u306b\u6c17\u3065\u304d\u307e\u3059\u3002\u3059\u3079\u3066\u3092\u899a\u3048\u308b\u5fc5\u8981\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u81ea\u5206\u304c\u5b9f\u7fd2\u3067\u51fa\u4f1a\u3063\u305f\u304c\u3093\u7a2e\u306e\u85ac\u304b\u3089\u4e00\u3064\u305a\u3064\u3001\u300c\u4f55\u3092\u72d9\u3046\u85ac\u304b\u300d\u300c\u3069\u3093\u306a\u8a66\u9a13\u3067\u8a8d\u3081\u3089\u308c\u305f\u304b\u300d\u3092\u78ba\u304b\u3081\u3066\u3044\u304f\u3068\u3001\u77e5\u8b58\u304c\u81ea\u7136\u3068\u3064\u306a\u304c\u3063\u3066\u3044\u304d\u307e\u3059\u3002<br \/>\n\u51fa\u5178<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.pmda.go.jp\/files\/000281577.pdf&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\" target=\"_blank\" rel=\"noopener\">\uff1aPMDA\u300c\u627f\u8a8d\u54c1\u76ee\u4e00\u89a7\uff08\u65b0\u533b\u85ac\u54c1\uff1a2026\u5e749\u6708\uff09\u300d\uff08\u5225\u8868\uff09\u00a0<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500<br \/>\n\u25a0 \u4eca\u9031\u306e\u4e00\u5831\uff08\u6ce8\u76ee\u8ad6\u6587\uff09\u3014\u4e73\u304c\u3093\uff0fADC\u3015<\/p>\n<p>&nbsp;<\/p>\n<p>\u514d\u75ab\u7642\u6cd5\u304c\u4f7f\u3048\u306a\u3044\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u306e\u4e00\u6b21\u6cbb\u7642 \u2015 \u7b2c\u2162\u76f8 TROPION-Breast02 \u8a66\u9a13<br \/>\nAnn Oncol. 2026;37(8):1066\u20131080.\uff0f\u7b2c\u2162\u76f8\u30fb\u56fd\u969b\u5171\u540c\u30fb\u975e\u76f2\u691c\u7121\u4f5c\u70ba\u5316\u6bd4\u8f03\u8a66\u9a13\uff08TROPION-Breast02\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>\u30fb\u5bfe\u8c61\u306f\u3001\u672a\u6cbb\u7642\u306e\u5c40\u6240\u518d\u767a\u624b\u8853\u4e0d\u80fd\u307e\u305f\u306f\u8ee2\u79fb\u6027\u306e\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u3067\u3001\u514d\u75ab\u7642\u6cd5\u304c\u6cbb\u7642\u306e\u9078\u629e\u80a2\u306b\u306a\u3089\u306a\u3044\u65b9\u3067\u3059\u3002<br \/>\n\u30fb2022\u5e745\u6708\u304b\u30892024\u5e746\u6708\u307e\u3067\u306b644\u4f8b\u304c\u767b\u9332\u3055\u308c\u3001\u30c0\u30c8\u30dd\u30bf\u30de\u30d6 \u30c7\u30eb\u30af\u30b9\u30c6\u30ab\u30f3\u7fa4323\u4f8b\uff086mg\/kg \u30923\u9031\u3054\u3068\u306b\u70b9\u6ef4\uff09\u3068\u3001\u62c5\u5f53\u533b\u304c\u9078\u3076\u5316\u5b66\u7642\u6cd5\u7fa4321\u4f8b\u306b1\u5bfe1\u3067\u5272\u308a\u4ed8\u3051\u3089\u308c\u307e\u3057\u305f\u3002\u5272\u308a\u4ed8\u3051\u306f\u3001\u5730\u57df\u3001\u7121\u75c5\u671f\u9593\u3001PD-L1 \u306e\u72b6\u614b\u3067\u5c64\u5225\u5316\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306f\u3001\u7121\u5897\u60aa\u751f\u5b58\u671f\u9593\uff08\u72ec\u7acb\u4e2d\u592e\u5224\u5b9a\uff09\u3068\u5168\u751f\u5b58\u671f\u9593\u306e2\u3064\u3067\u3059\u3002<br \/>\n\u30fb\u7121\u5897\u60aa\u751f\u5b58\u671f\u9593\u306e\u4e2d\u592e\u5024\u306f10.8\u304b\u6708\uff0895%CI 8.6\u301c13.0\uff09\u5bfe5.6\u304b\u6708\uff0895%CI 5.0\u301c7.0\uff09\u3001\u30cf\u30b6\u30fc\u30c9\u6bd40.57\uff0899%CI 0.44\u301c0.73\uff09\u3001P&lt;0.0001\u3067\u3057\u305f\u3014\u8ad6\u6587\u5831\u544a\u5024\u3015\u3002<br \/>\n\u30fb\u5168\u751f\u5b58\u671f\u9593\u306e\u4e2d\u592e\u5024\u306f23.7\u304b\u6708\uff0895%CI 19.8\u301c25.6\uff09\u5bfe18.7\u304b\u6708\uff0895%CI 16.0\u301c21.8\uff09\u3001\u30cf\u30b6\u30fc\u30c9\u6bd40.79\uff0895.01%CI 0.64\u301c0.98\uff09\u3001P=0.029\u3067\u3001\u5168\u751f\u5b58\u671f\u9593\u3067\u3082\u6709\u610f\u306a\u5ef6\u9577\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3014\u8ad6\u6587\u5831\u544a\u5024\u3015\u3002<br \/>\n\u30fb\u6cbb\u7642\u306b\u95a2\u9023\u3059\u308b Grade 3\u4ee5\u4e0a\u306e\u6709\u5bb3\u4e8b\u8c61\u306f33%\u5bfe29%\u3001\u6cbb\u7642\u306b\u95a2\u9023\u3059\u308b\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308b\u4e2d\u6b62\u306f4%\u5bfe7%\u3067\u3001\u6cbb\u7642\u306b\u95a2\u9023\u3059\u308b\u6b7b\u4ea1\u306f\u3069\u3061\u3089\u306e\u7fa4\u306b\u3082\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3014\u8ad6\u6587\u5831\u544a\u5024\u3015\u3002<br \/>\n\u30fb\u8457\u8005\u306b\u306f\u3001\u65e5\u672c\u304b\u3089\u798f\u5cf6\u770c\u7acb\u533b\u79d1\u5927\u5b66\u3001\u6771\u6d77\u5927\u5b66\u306e\u7814\u7a76\u8005\u3082\u52a0\u308f\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u81e8\u5e8a\u7684\u610f\u7fa9\uff1aPD-L1 \u967d\u6027\u306e\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u3067\u306f\u3001\u5316\u5b66\u7642\u6cd5\u306b\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\u3092\u52a0\u3048\u308b\u6cbb\u7642\u304c\u4e00\u6b21\u6cbb\u7642\u306e\u6a19\u6e96\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u514d\u75ab\u7642\u6cd5\u306e\u5bfe\u8c61\u3068\u306a\u3089\u306a\u3044\u65b9\u306e\u4e00\u6b21\u6cbb\u7642\u3067\u306f\u3001\u5316\u5b66\u7642\u6cd5\u304c\u4e2d\u5fc3\u3067\u3057\u305f\u3002\u305d\u306e\u65b9\u3005\u3092\u5bfe\u8c61\u306b\u3001\u5168\u751f\u5b58\u671f\u9593\u306e\u5ef6\u9577\u307e\u3067\u793a\u3057\u305f\u306e\u304c\u3053\u306e\u8a66\u9a13\u306e\u91cd\u307f\u3067\u3059\u3002\u4e00\u65b9\u3067\u3001Grade 3\u4ee5\u4e0a\u306e\u6709\u5bb3\u4e8b\u8c61\u306f\u5316\u5b66\u7642\u6cd5\u7fa4\u3068\u5927\u304d\u304f\u306f\u5909\u308f\u3089\u305a\u3001ADC \u3060\u304b\u3089\u526f\u4f5c\u7528\u304c\u5c11\u306a\u3044\u3001\u3068\u306f\u8a00\u3044\u5207\u308c\u307e\u305b\u3093\u3002\u95a2\u9023\u3059\u308b\u7dcf\u8aac\u3067\u3082\u3001\u627f\u8a8d\u3055\u308c\u305f ADC \u5168\u822c\u3067\u9593\u8cea\u6027\u80ba\u75be\u60a3\u3092\u524d\u3082\u3063\u3066\u76e3\u8996\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3060\u3068\u5f37\u8abf\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u300c\u52b9\u304f\u3053\u3068\u300d\u3068\u300c\u5b89\u5168\u306b\u7d9a\u3051\u3089\u308c\u308b\u3053\u3068\u300d\u306e\u4e21\u65b9\u3092\u78ba\u304b\u3081\u306a\u304c\u3089\u4f7f\u3046\u85ac\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u51fa\u5178\uff08PubMed \u53ce\u8f09\uff0fPMID: 41937088\uff09\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/doi.org\/10.1016\/j.annonc.2026.03.008&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\" target=\"_blank\" rel=\"noopener\">DOI: 10.1016\/j.annonc.2026.03.008<\/a> \uff08Dent R, et al. Ann Oncol 2026\uff09<br \/>\n\u95a2\u9023\uff08\u4e73\u304c\u3093\u306e\u4e00\u6b21\u6cbb\u7642\u30fb\u6839\u6cbb\u3092\u76ee\u6307\u3059\u6cbb\u7642\u3067\u306e ADC \u306e\u7dcf\u8aac\uff0fPMID: 42596749\uff09\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/doi.org\/10.1097\/CCO.0000000000001265&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\" target=\"_blank\" rel=\"noopener\">DOI: 10.1097\/CCO.0000000000001265<\/a> \uff08Odzer N, Tarantino P. Curr Opin Oncol 2026\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500<br \/>\n\u25a0 \u5b66\u4f1a\u30fb\u30bb\u30df\u30ca\u30fc\uff0f\u884c\u4e8b<\/p>\n<p>\u301c9\/30\uff08\u6c34\uff09\u6b63\u5348\u3000\u7b2c24\u56de\u65e5\u672c\u81e8\u5e8a\u816b\u760d\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\uff08JSMO2027\uff09\u4e00\u822c\u6f14\u984c\u306e\u52df\u96c6\u671f\u9593\u304c\u5ef6\u9577\u3055\u308c\u307e\u3057\u305f<br \/>\n2027\u5e743\u6708\u306b\u91d1\u6ca2\u3067\u958b\u304b\u308c\u308b\u65e5\u672c\u81e8\u5e8a\u816b\u760d\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u306e\u4e00\u822c\u6f14\u984c\u52df\u96c6\u304c\u30019\u670816\u65e5\uff08\u6c34\uff09\u6b63\u5348\u304b\u30899\u670830\u65e5\uff08\u6c34\uff09\u6b63\u5348\u307e\u3067\u5ef6\u9577\u3055\u308c\u307e\u3057\u305f\u3002\u4eca\u56de\u304b\u3089\u3001\u63a1\u629e\u3055\u308c\u305f\u6f14\u984c\u306e\u7b46\u982d\u6f14\u8005\u306f2027\u5e741\u670831\u65e5\u307e\u3067\u306b\u53c2\u52a0\u767b\u9332\u3092\u6e08\u307e\u305b\u308b\u3053\u3068\u304c\u5fc5\u9808\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<br \/>\n\u30fb\u4f1a\u671f\uff1a2027\u5e743\u670818\u65e5\uff08\u6728\uff09\u301c20\u65e5\uff08\u571f\uff09<br \/>\n\u30fb\u4f1a\u5834\uff1a\u77f3\u5ddd\u770c\u7acb\u97f3\u697d\u5802 \u4ed6\uff08\u77f3\u5ddd\u770c\u91d1\u6ca2\u5e02\uff09<br \/>\n\u30fb\u6f14\u984c\u52df\u96c6\uff1a2026\u5e749\u670830\u65e5\uff08\u6c34\uff09\u6b63\u5348\u307e\u3067\uff08\u5ef6\u9577\u5f8c\uff09<br \/>\n\u30fb\u4e3b\u50ac\uff1a\u516c\u76ca\u793e\u56e3\u6cd5\u4eba\u65e5\u672c\u81e8\u5e8a\u816b\u760d\u5b66\u4f1a\uff08\u4f1a\u9577\uff1a\u77e2\u91ce\u8056\u4e8c \u5148\u751f\u3014\u91d1\u6ca2\u5927\u5b66\u3015\uff09<br \/>\n\u30fb\u6f14\u984c\u52df\u96c6\u30da\u30fc\u30b8\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.c-linkage.co.jp\/jsmo2027\/cfa.html&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\">https:\/\/www.google.com\/url?q=https:\/\/www.c-linkage.co.jp\/jsmo2027\/cfa.html&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E<\/a><br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u5f53\u79d1\u3067\u3082\u3001\u533b\u5b66\u751f\u304c\u7b46\u982d\u306e\u6f14\u984c\u3092\u6e96\u5099\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u5b66\u4f1a\u767a\u8868\u3092\u8003\u3048\u3066\u3044\u308b\u5b66\u751f\u30fb\u7814\u4fee\u533b\u306e\u65b9\u3067\u3001\u6307\u5c0e\u3092\u53d7\u3051\u3089\u308c\u308b\u74b0\u5883\u3092\u63a2\u3057\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u5f53\u79d1\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>10\/10\uff08\u571f\uff09\u7b2c14\u56de \u65e5\u672c\u81e8\u5e8a\u816b\u760d\u5b66\u4f1a \u8fd1\u757f\u5730\u533a\u30bb\u30df\u30ca\u30fc\uff08\u7b2c8\u53f7\u304b\u3089\u7d99\u7d9a\u30fb\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u30fb\u7121\u6599\uff09<br \/>\n\u304c\u3093\u30b2\u30ce\u30e0\u30d7\u30ed\u30d5\u30a1\u30a4\u30ea\u30f3\u30b0\uff08CGP\uff09\u691c\u67fb\u3001\u5fae\u5c0f\u6b8b\u5b58\u75c5\u5909\uff08MRD\uff09\u3001\u5c02\u9580\u533b\u6a5f\u69cb\u8a8d\u5b9a\u306e\u304c\u3093\u85ac\u7269\u7642\u6cd5\u5c02\u9580\u533b\u5236\u5ea6\u3092\u53d6\u308a\u4e0a\u3052\u308b\u30bb\u30df\u30ca\u30fc\u3067\u3059\u3002\u5bfe\u8c61\u306f\u300c\u533b\u7642\u5f93\u4e8b\u8005\u306a\u3089\u3069\u306a\u305f\u3067\u3082\u300d\u3068\u3055\u308c\u3001\u5b66\u4f1a\u304b\u3089\u306e\u6848\u5185\u3067\u3082\u3001\u7814\u4fee\u533b\u3084\u30b3\u30e1\u30c7\u30a3\u30ab\u30eb\u30b9\u30bf\u30c3\u30d5\u306e\u53c2\u52a0\u3092\u6b53\u8fce\u3059\u308b\u3068\u66f8\u304b\u308c\u3066\u3044\u307e\u3059\u3002Web\u914d\u4fe1\u304c\u3042\u308b\u306e\u3067\u3001\u7fa4\u99ac\u304b\u3089\u3082\u53c2\u52a0\u3067\u304d\u307e\u3059\u3002<br \/>\n\u30fb\u65e5\u6642\uff1a2026\u5e7410\u670810\u65e5\uff08\u571f\uff0914:00\u301c16:30<br \/>\n\u30fb\u4f1a\u5834\uff1a\u5927\u962a\u5e02\u7acb\u7dcf\u5408\u533b\u7642\u30bb\u30f3\u30bf\u30fc \u90fd\u5cf6\u30bb\u30f3\u30bf\u30fc\u30d3\u30eb1\u968e \u5927\u4f1a\u8b70\u5ba4A\uff08\u73fe\u5730\u5b9a\u54e150\u540d\uff09\uff0bWeb\u914d\u4fe1<br \/>\n\u30fb\u5bfe\u8c61\uff1a\u533b\u7642\u5f93\u4e8b\u8005\u306a\u3089\u3069\u306a\u305f\u3067\u3082\uff08JSMO\u4f1a\u54e1\u8cc7\u683c\u4e0d\u554f\u3002\u7814\u4fee\u533b\u306e\u53c2\u52a0\u3082\u6b53\u8fce\uff09<br \/>\n\u30fb\u53c2\u52a0\u8cbb\uff1a\u7121\u6599\uff08\u53c2\u52a0\u767b\u9332\u30d5\u30a9\u30fc\u30e0\u304b\u3089\u4e8b\u524d\u767b\u9332\u3002\u767b\u9332\u7de0\u5207 2026\u5e7410\u67089\u65e5\u3014\u91d1\u3015\uff09<br \/>\n\u30fb\u4e3b\u50ac\uff1a\u516c\u76ca\u793e\u56e3\u6cd5\u4eba\u65e5\u672c\u81e8\u5e8a\u816b\u760d\u5b66\u4f1a<br \/>\n\u30fb\u30d7\u30ed\u30b0\u30e9\u30e0\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/www.jsmo.or.jp\/wp\/wp-content\/uploads\/dfca6d67d1b566f3909d724281967ebd.pdf&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\">https:\/\/www.google.com\/url?q=https:\/\/www.jsmo.or.jp\/wp\/wp-content\/uploads\/dfca6d67d1b566f3909d724281967ebd.pdf&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E<\/a><br \/>\n\u30fb\u53c2\u52a0\u767b\u9332\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/us02web.zoom.us\/webinar\/register\/WN_SwX_gQcXStOVtgIxnQ230g&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\">https:\/\/www.google.com\/url?q=https:\/\/us02web.zoom.us\/webinar\/register\/WN_SwX_gQcXStOVtgIxnQ230g&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E<\/a><br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u30b2\u30ce\u30e0\u691c\u67fb\u3084\u8840\u6db2\u3067\u8abf\u3079\u308b\u304c\u3093\u306e\u75d5\u8de1\uff08MRD\uff09\u306f\u3001\u3053\u306e\u6570\u5e74\u3067\u6025\u306b\u8eab\u8fd1\u306b\u306a\u3063\u305f\u8a71\u984c\u3067\u3059\u3002\u5c02\u9580\u533b\u5236\u5ea6\u306e\u8a71\u3068\u5408\u308f\u305b\u3066\u3001\u816b\u760d\u5185\u79d1\u533b\u306e\u3053\u308c\u304b\u3089\u3092\u8003\u3048\u308b\u6750\u6599\u306b\u306a\u308b\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>11\/21\uff08\u571f\uff09\u4e2d\u56fd\u30fb\u56db\u56fd\u5730\u533a\u30bb\u30df\u30ca\u30fc\u300111\/22\uff08\u65e5\uff09Best of ESMO 2026\uff08\u524d\u53f7\u304b\u3089\u7d99\u7d9a\uff09<br \/>\n\u524d\u53f7\u3067\u3054\u7d39\u4ecb\u3057\u305f2\u3064\u306e\u4f1a\u3082\u3001\u5f15\u304d\u7d9a\u304d\u7533\u8fbc\u307f\u3092\u53d7\u3051\u4ed8\u3051\u3066\u3044\u307e\u3059\u3002\u4e2d\u56fd\u30fb\u56db\u56fd\u5730\u533a\u30bb\u30df\u30ca\u30fc\u306f\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u958b\u50ac\u30fb\u53c2\u52a0\u8cbb\u7121\u6599\u30fb\u4f1a\u54e1\u8cc7\u683c\u4e0d\u554f\uff08\u7814\u4fee\u533b\u306e\u53c2\u52a0\u3082\u6b53\u8fce\u3001\u767b\u9332\u7de0\u5207\u306f11\u670816\u65e5\uff09\u3001Best of ESMO 2026 \u306f\u4eca\u5e74\u304b\u3089\u5b66\u751f\u30fb\u521d\u671f\u7814\u4fee\u533b\u304c\u7121\u6599\u3067\u53c2\u52a0\u3067\u304d\u307e\u3059\uff08\u7533\u8fbc\u6642\u306b\u5b66\u751f\u8a3c\u306a\u3069\u306e\u30a2\u30c3\u30d7\u30ed\u30fc\u30c9\u304c\u5fc5\u8981\uff09\u3002<br \/>\n\u30fb\u4e2d\u56fd\u30fb\u56db\u56fd\u5730\u533a\u30bb\u30df\u30ca\u30fc \u53c2\u52a0\u767b\u9332\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/forms.gle\/9gQiBqVmjwhmqHci7&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\">https:\/\/www.google.com\/url?q=https:\/\/forms.gle\/9gQiBqVmjwhmqHci7&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E<\/a><br \/>\n\u30fbBest of ESMO 2026 \u7533\u8fbc\uff1a<a href=\"https:\/\/www.google.com\/url?q=https:\/\/medicalprime.jp\/event\/boe2026\/&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E\">https:\/\/www.google.com\/url?q=https:\/\/medicalprime.jp\/event\/boe2026\/&amp;source=gmail&amp;ust=1790138332520000&amp;sa=E<\/a><br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u79cb\u304b\u3089\u51ac\u306b\u304b\u3051\u3066\u3001\u5b66\u751f\u30fb\u7814\u4fee\u533b\u304c\u53c2\u52a0\u3057\u3084\u3059\u3044\u5b66\u4f1a\u306e\u4f01\u753b\u304c\u7d9a\u304d\u307e\u3059\u3002\u6c17\u306b\u306a\u308b\u3082\u306e\u3092\u4e00\u3064\u9078\u3093\u3067\u3001\u4e88\u5b9a\u306b\u5165\u308c\u3066\u304a\u304f\u3068\u3088\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n<p>\u5f53\u79d1\u306e\u898b\u5b66\u30fb\u5b9f\u7fd2\u30fb\u9032\u8def\u76f8\u8ac7\u306f\u968f\u6642\u53d7\u3051\u4ed8\u3051\u3066\u3044\u307e\u3059<br \/>\n\u5916\u6765\u3084\u30ab\u30f3\u30d5\u30a1\u30ec\u30f3\u30b9\u306e\u898b\u5b66\u3001\u77ed\u671f\u306e\u5b9f\u7fd2\u306a\u3069\u3001\u5e0c\u671b\u306b\u5fdc\u3058\u3066\u65e5\u7a0b\u3092\u8abf\u6574\u3057\u307e\u3059\u3002\u5b66\u5e74\u3084\u6240\u5c5e\u306f\u554f\u3044\u307e\u305b\u3093\u3002\u304a\u554f\u3044\u5408\u308f\u305b\u306f\u816b\u760d\u5185\u79d1\u307e\u3067\u3002<br \/>\n\u5b66\u3073\u3069\u3053\u308d\uff1a\u3053\u306e\u8a18\u4e8b\u3067\u7d39\u4ecb\u3057\u3066\u3044\u308b\u30ab\u30f3\u30d5\u30a1\u30ec\u30f3\u30b9\u3084\u59d4\u54e1\u4f1a\u306e\u96f0\u56f2\u6c17\u306f\u3001\u898b\u5b66\u3067\u5b9f\u969b\u306b\u611f\u3058\u3066\u3044\u305f\u3060\u3051\u307e\u3059\u3002<\/p>\n<p>\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500\u2500<br \/>\n\u25a0 \u3072\u3068\u3053\u3068\u30b3\u30e9\u30e0 \u2015 \u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u304c\u300c2\u3064\u300d\u3042\u308b\u8a66\u9a13\u306e\u8aad\u307f\u65b9<\/p>\n<p>\u4eca\u56de\u306e TROPION-Breast02 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